Table 3 Anthropometric, stooling characteristics, intakes and abdominal findings in subjects who completed the study
CD-C, n = 18 | CD-I, n = 22 | |||||
|---|---|---|---|---|---|---|
Initiala | SD28 | SD84 | Initiala | SD28 | SD84 | |
Weight, kg | 17.8 ± 1.3 | 18.3 ± 1.4 | 19.2 ± 1.5b | 5.73 ± 0.35 | 6.40 ± 0.33 | 7.53 ± 0.27b |
WHO weight-for-age z-score | −0.81 ± 0.20 | −0.73 ± 0.22 | −0.50 ± 0.23c | −0.83 ± 0.29 | −0.64 ± 0.26 | −0.24 ± 0.20b |
Length, cm | 103.1 ± 4.3 | 103.5 ± 4.1 | 104.9 ± 4.2b | 60.4 ± 1.4 | 62.8 ± 1.3 | 66.9 ± 1.0b |
WHO length-for-age z-score | −1.68 ± 0.40 | −1.69 ± 0.36 | −1.64 ± 0.38 | −0.47 ± 0.31 | −0.34 ± 0.29 | −0.09 ± 0.24 |
Number of stools/dayd | 5.5 ± 1.0 | 5.2 ± 0.8 | 4.9 ± 1.0 | 3.5 ± 0.5 | 2.3 ± 0.3 | 1.5 ± 0.2b |
MRSCe | 1.5 ± 0.1 | 1.6 ± 0.2 | 1.7 ± 0.2 | 2.1 ± 0.1 | 2.3 ± 0.2 | 2.7 ± 0.2b |
Study feeding intake, mL/kg/day | 125 ± 14 | 123 ± 12 | 121 ± 13 | 165 ± 9 | 142 ± 9 | 130 ± 7f |
Energy intake from study feeding, kcal/kg/day | 101 ± 11 | 104 ± 12 | 101 ± 12 | 105 ± 6 | 95 ± 6 | 87 ± 5f |
Total energy intake, kcal/kg/day | 115 ± 12 | 116 ± 13 | 110 ± 12 | 110 ± 5 | 103 ± 5 | 104 ± 5 |
Physicians Evaluation of Abdominal Findings, number (%)g | ||||||
Subjective Complaints | ||||||
None - absent | 5 (28%) | 14 (76%) | 15 (83%) | -- | -- | -- |
Mild - complaints of nausea or abdominal pain, no change in activity | 8 (44%) | 4 (24%) | 3 (17%) | -- | -- | -- |
Moderate - frequent complaints of nausea or pain, decreased activity | 5 (28%) | 0 | 0 | -- | -- | -- |
Severe - patient in bed, crying or notably distressed | 0 | 0 | 0 | -- | -- | -- |
Objective Complaintsh | ||||||
None - absent | 0 | 1 (6%) | 1 (6%) | 5 (23%) | 17 (77%) | 22 (100%) |
Mild - 1 episode of emesis or 1 more diarrhea stool/day than usual | 0 | 3 (18%) | 2 (11%) | 1 (5%) | 1 (5%) | 0 |
Moderate – 2 to 3 episodes of emesis or 2–3 more diarrheal stools/day than usual or 1 of each/day | 3 (17%) | 4 (24%) | 6 (33%) | 5 (23%) | 3 (14%) | 0 |
Severe - > 3 episodes of emesis or > 3 diarrheal stools/day than usual or 2 of each/day | 15 (83%) | 10 (53%) | 9 (50%) | 11 (50%) | 1 (5%) | 0 |