Table 1 Formula milk versus donor milk for feeding preterm or low birth weight infants (Cochrane review)
From: DoMINO: Donor milk for improved neurodevelopmental outcomes
Author | Year | Subjects | Comparison | Blind | Primary outcome | Notes |
|---|---|---|---|---|---|---|
Davies[25] | 1977 | 68 preterm (28–36 weeks) | Term formula vs Donor Milk | No | Slower growth first month for Donor Milk | Uncertain group for 2 infants with mother’s own milk |
Gross[26] | 1983 | 67 preterm (27–33 weeks) | Term formula vs Donor Milk | No | Slower growth for term Donor Milk (not preterm Donor Milk) | Infants with feed intolerance/NEC withdrawn from growth analysis |
Lucas[27] | 1984 | 159 LBW (<1850Â g) | Preterm formula vs Donor Milk | No | Slower growth for Donor Milk; no neurodevelopmental difference | Â |
Lucas[28] | 1984 | 343 LBW (<1850Â g) | Preterm formula vs Donor Milk | No | No neurodevelopmental difference | Â |
Raiha[29] | 1976 | 106 LBW (<2100Â g) | Term formula vs Donor Milk | No | No difference in growth | Â |
Schanler[30] | 2005 | 173 preterm (<30Â weeks) | Term formula vs Fortified Donor Milk | Yes | Slower growth for Donor Milk, no difference in infection events | Only fortified Donor Milk study; 20% cross-over from Donor Milk to Formula |
Schultz[31] | 1980 | 20 preterm | Term formula vs Donor Milk | No | No difference in weight gain | Â |
Tyson[32] | 1983 | 81 LBW (<1500Â g) | Preterm formula vs Donor Milk | No | Slower growth for Donor Milk | Donor Milk not pasteurized; Randomized day 10; 5 affected infants withdrawn |