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Table 1 Formula milk versus donor milk for feeding preterm or low birth weight infants (Cochrane review)

From: DoMINO: Donor milk for improved neurodevelopmental outcomes

Author Year Subjects Comparison Blind Primary outcome Notes
Davies[25] 1977 68 preterm (28–36 weeks) Term formula vs Donor Milk No Slower growth first month for Donor Milk Uncertain group for 2 infants with mother’s own milk
Gross[26] 1983 67 preterm (27–33 weeks) Term formula vs Donor Milk No Slower growth for term Donor Milk (not preterm Donor Milk) Infants with feed intolerance/NEC withdrawn from growth analysis
Lucas[27] 1984 159 LBW (<1850 g) Preterm formula vs Donor Milk No Slower growth for Donor Milk; no neurodevelopmental difference  
Lucas[28] 1984 343 LBW (<1850 g) Preterm formula vs Donor Milk No No neurodevelopmental difference  
Raiha[29] 1976 106 LBW (<2100 g) Term formula vs Donor Milk No No difference in growth  
Schanler[30] 2005 173 preterm (<30 weeks) Term formula vs Fortified Donor Milk Yes Slower growth for Donor Milk, no difference in infection events Only fortified Donor Milk study; 20% cross-over from Donor Milk to Formula
Schultz[31] 1980 20 preterm Term formula vs Donor Milk No No difference in weight gain  
Tyson[32] 1983 81 LBW (<1500 g) Preterm formula vs Donor Milk No Slower growth for Donor Milk Donor Milk not pasteurized; Randomized day 10; 5 affected infants withdrawn
  1. Quigley MA, Henderson G, Anthony MY, McGuire W. Formula milk versus donor breast milk for feeding preterm or low birth weight infants. Cochrane Database Syst Rev 2007:CD002971.