Table 1 Eligibility criteria for iCATS

Parental and child consent in CATS;

History of head trauma or loss of consciousness;

Completed Wave 1 of CATS in full, i.e., parent/guardian q’s, and child q’s, anthropometric measurements, and saliva sample;

History of clinically significant developmental or intellectual disorder;

Child aged between 8.5 and 9.5 years at the time of their CATSparticipation;

Clinically significant DHEA, DHEA-S, Testosterone;

Written consent provided by parent for their own participation;

Indications of claustrophobia;

Written consent provided by the parent and the child for the child’s participation; and,

Long-term use of steroidal or amphetamine based medications;

Verbal consent provided by the child.

Short-term current use (i.e., < 2 weeks) of amphetamines;

Short-term current use of steroidal medications will be reviewed on a case-by-case basis;

Presence or likelihood of internal or external non-removable ferrous metals;

Inability or unwillingness of participant or parent/guardian to provide informed consent.