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Table 1 Antimicrobial susceptibility patterns of the four major BOX-PCR profiles of ESBL-Kp in a NICU, Larissa, Greece

From: Successful control of a neonatal outbreak caused mainly by ST20 multidrug-resistant SHV-5-producing Klebsiella pneumoniae, Greece

BOX-PCR profilea

MLSTST

 

MIC range (mg/L)b

 

AMP

AMP/SUL

CTX

CAZ

ATM

IMP

MER

ERT

CIP

TOB

GM

TSX

NICU (n = 26)

P1 (16)

ST20

≥32

≤2- 16

≤1- ≥64

8- ≥64

8- ≥64

≤1

≤0.25

≤0.5

≤0.25

≥16

≥16

≤20

P2 (8)

ST1114

≥32

≤2

≤2- ≥64

16- ≥64

4- ≥64

≤1

≤0.25

≤0.5

≤0.25

≥16

≥16

≤20

Non-NICU (n = 38)

P5 (12)

ST258

≥32

8- ≥32

16

≥64

≥64

≤1

≤0.25

≤0.5

≥4

≤1-16

≥16

≤20- ≥320

P6 (16)

ST101

≥32

≥32

≥64

16- ≥64

32- ≥64

≤1

≤0.25

≤0.5

≥4

8- ≥16

≤1-8

≤20- ≥320

  1. aIn parenthesis, the number of isolates identified in each of the four major BOX-PCR profiles is shown.
  2. bAMP: ampicillin, AMP/SUL: ampicillin/sulbactam, ATM: aztreonam, CAZ: ceftazidime, CIP: ciprofloxacin, CTX: cefotaxime, ERT: ertapenem, GM: gentamycin, IMP: imipenem, MER: meropenem, TOB: tobramycin, TSX: trimethoprim/sulfamethoxazol.