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Table 1 Antimicrobial susceptibility patterns of the four major BOX-PCR profiles of ESBL-Kp in a NICU, Larissa, Greece

From: Successful control of a neonatal outbreak caused mainly by ST20 multidrug-resistant SHV-5-producing Klebsiella pneumoniae, Greece

BOX-PCR profilea MLSTST   MIC range (mg/L)b  
AMP AMP/SUL CTX CAZ ATM IMP MER ERT CIP TOB GM TSX
NICU (n = 26)
P1 (16) ST20 ≥32 ≤2- 16 ≤1- ≥64 8- ≥64 8- ≥64 ≤1 ≤0.25 ≤0.5 ≤0.25 ≥16 ≥16 ≤20
P2 (8) ST1114 ≥32 ≤2 ≤2- ≥64 16- ≥64 4- ≥64 ≤1 ≤0.25 ≤0.5 ≤0.25 ≥16 ≥16 ≤20
Non-NICU (n = 38)
P5 (12) ST258 ≥32 8- ≥32 16 ≥64 ≥64 ≤1 ≤0.25 ≤0.5 ≥4 ≤1-16 ≥16 ≤20- ≥320
P6 (16) ST101 ≥32 ≥32 ≥64 16- ≥64 32- ≥64 ≤1 ≤0.25 ≤0.5 ≥4 8- ≥16 ≤1-8 ≤20- ≥320
  1. aIn parenthesis, the number of isolates identified in each of the four major BOX-PCR profiles is shown.
  2. bAMP: ampicillin, AMP/SUL: ampicillin/sulbactam, ATM: aztreonam, CAZ: ceftazidime, CIP: ciprofloxacin, CTX: cefotaxime, ERT: ertapenem, GM: gentamycin, IMP: imipenem, MER: meropenem, TOB: tobramycin, TSX: trimethoprim/sulfamethoxazol.