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Table 1 Presence of a code for CMV-associated conditions a among all infants, infants with CMV-specific testing, infants with non-specific testing, and infants with a diagnostic code for CMV, MarketScan 2011 b

From: Laboratory testing and diagnostic coding for cytomegalovirus among privately insured infants in the United States: a retrospective study using administrative claims data

CMV-associated conditiona All Infants Infants with CMV-specific testingc Infants with Non-specific testingd Infants with an ICD-9-CM code for congenital CMV infection or CMV disease
N=368,266 N=229 N=1,091 N=61
# (%) # (%) # (%) # (%)
Chorioretinitis 13 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
Encephalitis 12 (0.0) 0 (0.0) 3 (0.3) 0 (0.0)
Hepatomegaly 45 (0.1) 5 (2.2) 1 (0.1) 0 (0.0)
Jaundice 110,997 (30.1) 54 (23.6) 361 (33.1) 11 (18.0)
Low Birth Weight 33,933 (9.2) 139 (60.7) 266 (24.4) 24 (39.3)
Microcephaly 115 (0.0) 5 (2.2) 7 (0.6) 3 (4.9)
Other Congenital Anomalies of Nervous System 988 (0.3) 24 (10.5) 28 (2.6) 4 (6.6)
Petechiae 1,650 (0.5) 1 (0.4) 2 (0.2) 1 (1.6)
Seizures 1,057 (0.3) 21 (9.2) 55 (5.0) 4 (6.6)
Splenomegaly 10 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
Thrombocytopenia 1,120 (0.3) 36 (15.7) 40 (3.7) 5 (8.2)
Any of the above 11 CMV-associated conditions 136,857 (37.2) 187 (81.7) 599 (54.9) 37 (60.7)
None of the above 11 CMV-associated conditions 231,409 (62.8) 42 (18.3) 492 (45.1) 24 (39.3)
  1. aSee Additional file 1: Table S1 for ICD-9-CM and CPT codes used to identify CMV-associated conditions.
  2. bInfants are defined as enrollees ≤ 1 month of age with ≥1 medical claim within 30 days of a newborn code (defined as either a code for live birth, or observation and evaluation of newborns and infants; codes defined in Additional file 1: Table S1).
  3. cCMV-specific testing includes CMV serologic testing (CMV IgG, CMV IgM, and CMV EIA), CMV DFA, and CMV PCR testing. (See Additional file 1: Table S1 for CPT codes).
  4. dNon-specific testing includes viral culture, molecular diagnostics, or infectious agent detection. (See Additional file 1: Table S1 for CPT codes).