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Table 3 The prevalence of cardiometabolic risk factors (CRF) of the children and adolescents participating in HELIOS, for all participants together and stratified according to SDS-BMI group

From: Cardiometabolic risk factors and quality of life in severely obese children and adolescents in the Netherlands

 

Total (n = 80)

SDS-BMI < median (n = 39)

SDS-BMI >= median (n = 41)

OR (95% CI)

High triglycerides

9 (11.2)

3 (7.7)

6 (14.6)

2.47 (0.42, 14.64)

Low HDL-cholesterol

52 (65.0)

24 (61.5)

28 (68.3)

1.49 (0.55, 4.94)

Hypertension

25 (31.2)

9 (23.1)

16 (39.0)

5.51 (1.37, 22.18)*

Impaired fasting glucose

1 (1.2)

1 (2.6)

0 (0)

-

Impaired glucose tolerance

5 (6.2)

4 (10.3)

1 (2.4)

-

DMII

0 (0.0)

-

-

-

High HOMA-IR

30 (37.5)

9 (23.1)**

21 (51.2)**

5.35 (1.39, 20.63)*

1 CRF (only obesity)

16 (20.0)

10 (25.6)

6 (14.6)

NA

2 CRF (1 in addition to obesity)

39 (48.8)

18 (46.2)

21 (51.2)

NA

>= 3 CRFs (>= 2 in addition to obesity)

25 (31.3)

11 (28.2)

14 (34.1)

NA

  1. Data are n (% of total) and OR with 95% CI.
  2. OR – Odds Ratio; SDS-BMI – standard deviation of body mass index; CI – confidence interval; HDL – High Density Lipoprotein; HOMA-IR – homeostasis model assessment for insulin resistance: DMII – Diabetes Mellitus type II.
  3. Reference cut off points cardiometabolic risk from ‘The metabolic syndrome in children and adolescents – an IDF consensus report’ by Zimmet et al. [27].
  4. Reference cut off points HOMA-IR from ‘Insulin resistance in obese children and adolescents: HOMA-IR cut-off levels in the prepubertal and pubertal periods’ by Kurtoğlu et al. [25], ‘Homeostasis model assessment is more reliable than the fasting glucose/insulin ratio and quantitative insulin sensitivity check index for assessing insulin resistance among obese children and adolescents’ by Keskin et al. for postpubertal stage [26].
  5. CRFs are based on the IDF criteria including obesity, high triglycerides, low HDL-cholesterol, hypertension, impaired fasting glucose, impaired glucose tolerance and DMII. Since all participants fulfilled the IDF criterion for obesity, none of the participants had zero CRF. Participants with 1 CRF only had obesity and none of the other CRFs. Participants with 2 CRFs had 1 CRF in addition to obesity. Participants with 3 or more CRFs had 2 or more CRFS in addition to obesity. HOMA-IR is not taken into account in the number of CRFs.
  6. Median is 3.49.
  7. - Insufficient sample size.
  8. * P value <0.05.
  9. ** P value < 0.01.
  10. NA Not applicable.
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BMC Pediatrics

ISSN: 1471-2431

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