Table 2 Anthropometric and laboratory measurements of the children and adolescents participating in HELIOS, for all participants together and stratified according to SDS-BMI group and Spearman’s rank correlations
|  | Total (n = 80) | SDS-BMI < median (n = 39) | SDS-BMI >= median (n = 41) | Spearman’s R with SDS-BMI | Spearman’s R with EQ-5D |
|---|---|---|---|---|---|
Age (y) | 14.8 (2.3) | 14.4 (2.4) | 15.2 (2.2) | 0.19 | 0.05 |
Male/Female (%) | 33.8/66.2 | 17.9/82.1** | 48.8/51.2** | NA | NA |
SDS-BMI | 3.4 (0.4) | 3.1 (0.2)** | 3.7 (0.3)** | - | −0.03 |
SDS-waist circumference | 3.6 (0.3) | 3.4 (0.2)** | 3.8 (0.3)** | 0.80** | −0.07 |
BIS | Â | Â | Â | Â | Â |
  Fat mass (%) | 52.3 (4.4) | 50.5 (3.8)** | 53.9 (4.4)** | 0.32** | −0.13 |
Systolic blood pressure (mmHg) | 121.9 (12.8) | 117.5 (11.1)** | 126.1 (13.0)** | 0.37** | −0.09 |
Diastolic blood pressure (mmHg) | 76.8 (11.1) | 74.9 (9.4) | 78.7 (12.4) | 0.19 | 0.03 |
Puberty stage (%)1 | Â | Â | Â | Â | Â |
  Prepubertal | 8.8 | 12.8 | 4.9 | NA | NA |
  Pubertal | 48.8 | 53.8 | 43.9 | NA | NA |
  Postpubertal | 42.5 | 33.3 | 51.2 | NA | NA |
Fasting plasma insulin (pmol/L) | 98.6 (65.1) | 72.6 (40.4)** | 122.7 (74.4)** | 0.49** | −0.12 |
Fasting plasma glucose (mmol/L) | 4.7 (0.3) | 4.6 (0.3)* | 4.8 (0.3)* | 0.19 | −0.10 |
2-h plasma glucose (mmol/L) | 5.8 (1.2) | 5.8 (1.4) | 5.9 (0.9) | 0.14 | −0.22†|
Total cholesterol (mmol/L) | 3.8 (0.7) | 3.7 (0.8) | 3.8(0.7) | 0.09 | −0.13 |
HDL-cholesterol (mmol/L) | 1.0 (0.2) | 1.1 (0.2) †| 1.0 (0.2) †| −0.22†| −0.10 |
LDL-cholesterol (mmol/L) | 2.3 (0.6) | 2.2 (0.6) | 2.3 (0.7) | 0.00 | −0.08 |
Triglycerides (mmol/L) | 1.0 (0.6) | 0.8 (0.4)** | 1.2 (0.6)** | 0.37** | −0.18 |
HS-CRP (mg/l) | 5.0 (4.6) | 4.4 (4.6) | 5.5 (4.6) | 0.22 | 0.07 |
HbA1C (DCCT %) | 5.5 (0.3) | 5.5(0.3) | 5.5 (0.2) | 0.05 | 0.07 |
HOMA-IR | 3.0 (2.1) | 2.2 (1.3)** | 3.8 (2.4)** | 0.48** | −0.15 |