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Table 2 List of the most 10 most used active substances in the population study and in the three regions ordered by % of treated children

From: Drug use profile in outpatient children and adolescents in different Italian regions

  % of treated children
  Study population Regions
  Lombardy Lazio Puglia
amoxicillin clavulanate 41.6 43.2 (1) 40.2 (1) 41.5 (1)
beclometasone 23.5 18.8 (3) 26.2 (2) 25.5 (2)
clarithromycin 18.5 14.3 (5) 18.8 (3) 22.5 (3)
amoxicillin 18.2 27.7 (2) 13.3 (7) 13.7 (6)
salbutamol 14.8 15.2 (4) 17.9 (4) 11.2 (7)
cefixime 13.8 6.6 (9) 15.7 (5) 19.2 (4)
azithromycin 12.8 10.4 (6) 12.8 (8) 15.2 (5)
betametasone 9.7 7.2 (8) 13.6 (6) 8.3 (9)
cefaclor 8.0 7.5 (7) 9.2 (9) 7.2 (11)
cetirizine 5.9 5.8 (10) 6.6 (11) 5.4 (15)
  0-5 years old Lombardy Lazio Puglia
amoxicillin clavulanate 48.6 49.5 (1) 46.1 (1) 49.9 (1)
beclometasone 31.5 25.9 (3) 36.4 (2) 36.7 (2)
amoxicillin 27.5 37.0 (2) 19.4 (5) 18.4 (5)
salbutamol 22.4 21.6 (4) 27.1 (3) 18.1 (6)
clarithromycin 20.9 14.6 (5) 23.6 (4) 30.1 (3)
cefixime 13.5 6.7 (11) 18.4 (7) 21.2 (4)
betametasone 13.5 11.8 (6) 18.6 (6) 10.8 (12)
azithromycin 12.8 9.8 (8) 13.6 (8) 17.9 (7)
cefaclor 11.7 11.5 (7) 12.7 (9) 11.0 (10)
flunisolide 7.9 7.7 (9) 7.8 (11) 8.9 (14)
  6-11 years old Lombardy Lazio Puglia
amoxicillin clavulanate 41.7 42.6 (1) 40.9 (1) 41.1 (1)
beclometasone 19.8 15.8 (3) 22.8 (2) 23.0 (2)
clarithromycin 16.2 14.2 (4) 17.0 (3) 18.7 (4)
amoxicillin 16.2 23.3 (2) 9.9 (9) 11.3 (6)
cefixime 12.8 6.6 (8) 15.5 (4) 19.8 (3)
azithromycin 12.7 10.8 (6) 12.8 (6) 15.5 (5)
salbutamol 12.5 12.5 (5) 15.4 (5) 9.4 (7)
betametasone 8.1 5.3 (10) 11.7 (7) 8.6 (8)
cefaclor 7.8 6.6 (9) 10.0 (8) 7.6 (10)
cetirizine 7.5 7.7 (7) 8.1 (10) 6.8 (12)
  12-17 years old Lombardy Lazio Puglia
amoxicillin clavulanate 31.9 33.2 (1) 30.5 (1) 31.5 (1)
clarithromycin 14.8 13.7 (3) 13.8 (3) 17.5 (2)
beclometasone 12.8 10.2 (5) 15.0 (2) 14.4 (4)
amoxicillin 12.6 17.2 (2) 8.2 (7) 10.5 (6)
azithromycin 11.3 11.0 (4) 11.7 (5) 11.4 (5)
cefixime 10.9 6.4 (8) 12.0 (4) 16.0 (3)
salbutamol 6.5 7.5 (6) 7.3 (8) 4.5 (9)
cetirizine 5.6 6.5 (7) 5.3 (9) 4.7 (8)
betametasone 4.7 1.8 (15) 8.3 (6) 5.1 (7)
levocetirizine 4.6 4.5 (9) 5.0 (10) 4.3 (10)
  1. The numbers in brackets represent the rank corresponding to each active substance in each region.