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Table 3 Admission CD11b and CD64 (%) for neutrophils, monocytes, and lymphocytes in 3 groups of critically ill children compared to healthy controls

From: CD64-Neutrophil expression and stress metabolic patterns in early sepsis and severe traumatic brain injury in children

 

Control

TBI

Sepsis

Severe sepsis

p value

 

Values are medians (ranges)

 

Neutrophils

CD11b (%)

99.6 (98–100)

98.9 (93–100)

99 (92.6-99.9)

99.6 (96.3-100)

0.29

CD64 (%)

0.9 (0.1-4.3) b,c,d

5.5 (3–11.3) c,e,f

78.8 (25.7-97.3) b,e

81.2 (17.5-97.8) d,f

0.0001a

Monocytes

CD11b (%)

96 (86–99)

96.4 (92–99)

95 (52–99)

87.4 (24–97)

0.11

CD64 (%)

87.4 (78–94)

87.9 (87–97)

90.9 (42–99)

87.3 (18–94)

0.52

Lymphocytes

CD11b (%)

22.9 (7.7-36.5)

18.3 (8.2-39.5)

16.8 (7.3-42)

9.3 (0.9-33.5)

0.043a

CD64 (%)

0.1 (0–2.6) b,c

0.6 (0.1-3.8) c

0.82 (0.3-1.5) b

0.25 (0.1-2.9)

0.01a

  1. Results are given as Median (range).
  2. a Statistically significant differences, Kruskal-Wallis test.
  3. b –f Post-hoc Mann–Whitney U-test between 2 groups (p < 0.03).
  4. TBI, Traumatic Brain Injury.