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Table 2 Admission acute phase proteins, platelets, and metabolic indices in children with SIRS compared to healthy controls

From: CD64-Neutrophil expression and stress metabolic patterns in early sepsis and severe traumatic brain injury in children

  Control TBI Sepsis Severe sepsis p value
  Values: medians (ranges)  
CRP (mg/dl) 0.3 (0.1-0.7) b,c,d 0.3 (0.3-11) c,e,f 6.4 (0.5-15) d,e 12.8 (3.1-41) b,f 0.0001a
PCT (ng/ml) 0.2 (0.1-0.4) b,c,d 0.5 (0.1-2) c,e,f 8 (0.3-12) d,e 11.5 (0.3-12) b,f 0.0001a
WBC 9.7 (8.4-11) 12.3 (4.4-28) 20.8 (2–43) 9.9 (1.5-47) 0.31
Platelets (K/μl) 256 (212–300) 288 (135–518) 285 (105–801) 215 (24–451) 0.33
Glucose (mg/dl) 83 (74–108) b,c,d 134 (71–243) c 115 (65–202) d 118 (77–153) b 0.002a
TG (mg/dl) 71.8 (33–150) b,d 79.2 (27–175) e,f 151.7 (80–326) d,e 209.1 (34–591) b,f 0.007a
TC (mg/dl) 171.3 (133–235) b,c,d 132 (98–166) c, f 125.2 (56–208) d 100.6 (45–150) b, f 0.0001a
LDL (mg/dl) 98.1 (57–155) b,c,d 72.2 (41–110) c f 66.2 (15–111) d,g 33.4 (13–63) b,f,g 0.0001a
HDL (mg/dl) 58.7 (45–76) b,c,d 45.3 (24–62) c,e f 27.3 (12–57) d,e 29.5 9–62) b,f 0.0001a
TC/HDL (ratio) 2.9 (2.3-3.8) b,d 3.1 (2.1-5.2) c f 5.0 (3–8.7) d,c 5.5 (2.67-12.1) b,f 0.05a
  1. Results are given as Median (range).
  2. a Statistically significant differences, Kruskal-Wallis test.
  3. b –g Post-hoc Mann–Whitney U-test between 2 groups (p < 0.05).
  4. SIRS, systemic inflammatory response syndrome; TBI, Traumatic Brain Injury; CRP, C-Reacting Protein; PCT, Procalcitonin; TG, Triglycerides; TC, Total Cholesterol; LDL, Low-Density-Lipoproteins; HDL-Density-Lipoproteins; WBC, White Blood Cells.