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Table 2 Admission acute phase proteins, platelets, and metabolic indices in children with SIRS compared to healthy controls

From: CD64-Neutrophil expression and stress metabolic patterns in early sepsis and severe traumatic brain injury in children

 

Control

TBI

Sepsis

Severe sepsis

p value

 

Values: medians (ranges)

 

CRP (mg/dl)

0.3 (0.1-0.7) b,c,d

0.3 (0.3-11) c,e,f

6.4 (0.5-15) d,e

12.8 (3.1-41) b,f

0.0001a

PCT (ng/ml)

0.2 (0.1-0.4) b,c,d

0.5 (0.1-2) c,e,f

8 (0.3-12) d,e

11.5 (0.3-12) b,f

0.0001a

WBC

9.7 (8.4-11)

12.3 (4.4-28)

20.8 (2–43)

9.9 (1.5-47)

0.31

Platelets (K/μl)

256 (212–300)

288 (135–518)

285 (105–801)

215 (24–451)

0.33

Glucose (mg/dl)

83 (74–108) b,c,d

134 (71–243) c

115 (65–202) d

118 (77–153) b

0.002a

TG (mg/dl)

71.8 (33–150) b,d

79.2 (27–175) e,f

151.7 (80–326) d,e

209.1 (34–591) b,f

0.007a

TC (mg/dl)

171.3 (133–235) b,c,d

132 (98–166) c, f

125.2 (56–208) d

100.6 (45–150) b, f

0.0001a

LDL (mg/dl)

98.1 (57–155) b,c,d

72.2 (41–110) c f

66.2 (15–111) d,g

33.4 (13–63) b,f,g

0.0001a

HDL (mg/dl)

58.7 (45–76) b,c,d

45.3 (24–62) c,e f

27.3 (12–57) d,e

29.5 9–62) b,f

0.0001a

TC/HDL (ratio)

2.9 (2.3-3.8) b,d

3.1 (2.1-5.2) c f

5.0 (3–8.7) d,c

5.5 (2.67-12.1) b,f

0.05a

  1. Results are given as Median (range).
  2. a Statistically significant differences, Kruskal-Wallis test.
  3. b –g Post-hoc Mann–Whitney U-test between 2 groups (p < 0.05).
  4. SIRS, systemic inflammatory response syndrome; TBI, Traumatic Brain Injury; CRP, C-Reacting Protein; PCT, Procalcitonin; TG, Triglycerides; TC, Total Cholesterol; LDL, Low-Density-Lipoproteins; HDL-Density-Lipoproteins; WBC, White Blood Cells.