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Table 5 Differences in pregnancy complications between the controls, sporadic PPD1, and familial polydactyly (all types)

From: Epidemiology of isolated preaxial polydactyly type I: Data from the Polish Registry of Congenital Malformations (PRCM)

Characteristics Controls Sporadic PPD1 Familial Polydactyly Sporadic vs. Controls Familial vs. Controls Sporadic vs. Familial
N = 303$ N = 459$ N = 353$
Count (%) Count (%) Count (%) P-value P-value P-value
(Fisher's Exact Test) (Fisher's Exact Test) (Fisher's Exact Test)
Pregnancy pathology
 Oligohydramnios 0 (0%) 7 (1.5%) 6 (1.7%) 0.03 0.02 0.84 (NS)
 Polyhydramnios 0 (0%) 0 (0%) 4 (1.1%) 1.00 (NS) 0.09 (NS) 0.035
 Gestosis 13 (4.3%) 15 (3.3%) 9 (2.5%) 0.45 (NS) 0.22 (NS) 0.56 (NS)
Upper respiratory tract infections during 1st trimester of pregnancy 5 (1.7%) 19 (4.1%) 13 (3.7%) 0.049 0.11 (NS) 0.76 (NS)
Urinary system infections during 1st trimester of pregnancy 3 (1%) 5 (1.1%) 3 (0.8%) 0.90 (NS) 0.88 (NS) 0.77 (NS)
Mother’s chronic diseases
 Hypothyroidism 0 (0%) 4 (0.9%) 2 (0.6%) 0.13 (NS) 0.30 (NS) 0.64 (NS)
 Epilepsy 1 (0.3%) 8 (1.7%) 0 (0%) 0.08 (NS) 0.46 (NS) 0.01
Smoking during 1st trimester of pregnancy 22 (7.3%) 39 (8.5%) 25 (7.1%) 0.91 (NS) 0.33 (NS) 0.32 (NS)
Exposure to ionizing radiation during 1st trimester of pregnancy 1 (0.3%) 2 (0.4%) 1 (0.3%) 0.99 (NS) 0.80 (NS) 0.75 (NS)
  1. $ Marginal totals for some variables may be different because of missing values.
  2. NS: Not significant.