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Table 5 Differences in pregnancy complications between the controls, sporadic PPD1, and familial polydactyly (all types)

From: Epidemiology of isolated preaxial polydactyly type I: Data from the Polish Registry of Congenital Malformations (PRCM)

Characteristics

Controls

Sporadic PPD1

Familial Polydactyly

Sporadic vs. Controls

Familial vs. Controls

Sporadic vs. Familial

N = 303$

N = 459$

N = 353$

Count (%)

Count (%)

Count (%)

P-value

P-value

P-value

(Fisher's Exact Test)

(Fisher's Exact Test)

(Fisher's Exact Test)

Pregnancy pathology

 Oligohydramnios

0 (0%)

7 (1.5%)

6 (1.7%)

0.03

0.02

0.84 (NS)

 Polyhydramnios

0 (0%)

0 (0%)

4 (1.1%)

1.00 (NS)

0.09 (NS)

0.035

 Gestosis

13 (4.3%)

15 (3.3%)

9 (2.5%)

0.45 (NS)

0.22 (NS)

0.56 (NS)

Upper respiratory tract infections during 1st trimester of pregnancy

5 (1.7%)

19 (4.1%)

13 (3.7%)

0.049

0.11 (NS)

0.76 (NS)

Urinary system infections during 1st trimester of pregnancy

3 (1%)

5 (1.1%)

3 (0.8%)

0.90 (NS)

0.88 (NS)

0.77 (NS)

Mother’s chronic diseases

 Hypothyroidism

0 (0%)

4 (0.9%)

2 (0.6%)

0.13 (NS)

0.30 (NS)

0.64 (NS)

 Epilepsy

1 (0.3%)

8 (1.7%)

0 (0%)

0.08 (NS)

0.46 (NS)

0.01

Smoking during 1st trimester of pregnancy

22 (7.3%)

39 (8.5%)

25 (7.1%)

0.91 (NS)

0.33 (NS)

0.32 (NS)

Exposure to ionizing radiation during 1st trimester of pregnancy

1 (0.3%)

2 (0.4%)

1 (0.3%)

0.99 (NS)

0.80 (NS)

0.75 (NS)

  1. $ Marginal totals for some variables may be different because of missing values.
  2. NS: Not significant.