Table 2 Main demographic and clinical characteristics of the study population
IgE mediated cow’s milk allergy n=29 | Non-IgE-mediated cow’s milk allergy n=31 | |
|---|---|---|
Sex, m (%) | 20 (69) | 24 (77.4) |
Age, m (95% CI) | 35 (31.0–38.9) | 39 (35.7–42.3) |
Volume of milk eliciting positive challenge, ml (95% CI) | 6 (1.9–10.2) | 144.4 |
Time of onset of reactions, minutes (95 % CI) | 48.1 (36.1–60.0) | 1843.5 (1618.3–2068.8) |
Concomitant multiple food allergies, n (%) | 24 (82.7) | 23 (74.1) |
·Hen’s egg, n (%) | 16 (66.7) | 5 (21.7) |
·Soy, n (%) | 3 (12.5) | 11 (47.8) |
·Peanut, n (%) | 10 (41.7) | 0 |
·Wheat, n (%) | 5 (20.8) | 8 (34.8) |
·Tree nut, n (%) | 3 (12.5) | 0 |
Gastrointestinal symptoms, n (%) | 12 (41.4) | 16 (51.6) |
·Vomiting, n (%) | 9 (31) | 11 (35.5) |
·Diarrhea, n (%) | 4 (13.8) | 20 (64.5) |
·Hematochezia, n (%) | 0 | 2 (6.4) |
Cutaneous symptoms, n (%) | 14 (48.3) | 8 (2.6) |
·Atopic dermatitis, n (%) | 10 (71.4) | 8 (100) |
·Urticaria | 4 (28.6) | - |
Respiratory symptoms, n (%) | 14 (48.3) | 0 |
Anaphylaxis, n (%) | 6 (20.7) | 0 |
Positive serum specific IgE to CMP, n (%) | 26 (89.6) | 0 |
Positive skin prick test to CMP, n (%) | 28 (96.5) | 0 |
Positive atopy patch test to CMP, n (%) | 0 | 27 (87) |