Skip to main content

Table 2 Overview of selected and used predictors in models

From: Clinical prediction models for bronchopulmonary dysplasia: a systematic review and external validation study

Study

Cohen [12]

Hakulinen [13]

Sinkin [14]

Palta [26]

Parker [27]

Corcoran [28]

Ryan 1994 [29]

Rozycki [30]

Ryan 1996 [31]

Romagnoli [32]

Yoder [33]

Kim [34]

Cuhna [35]

Choi [36]

Henderson-Smart [37]

Bhering [38]

Amblavanan [39]

Laughon [40]

Subhedar [41]

Srisuparp [42]

Choukroun [43]

Greenough [44]

Fowlie [45]

Hentschel [46]

Chein [47]

May [48]

Total % (n = 26)

Total number of predictors considered

NA

19

79

NA

14

16

9

16

10

Un

7

27

20

Un

21

66

26

15

NA

19

NA

NA

41

5

12

NA

 

Total number of predictors selected

2

5

4

8

7

8

4

5

3

3

6

8

4

3

3

4

6

6

NA

2

NA

NA

6

5

12

NA

 

Selected predictors

                           

Clinical

                           

Gestational age

  

x

 

x

x

x

x

 

x

x

x

x

x

x

x

 

x

x

 

x

x

x

 

x

 

69 (18)

Birth weight

  

x

x

x

x

  

X

x

x

x

  

x

 

x

x

x

 

x

x

x

x

  

62 (16)

Small for gestational age

                        

x

 

4 (1)

Race/ethnicity

    

x

            

x

        

8 (2)

>15 % Birth weight loss

               

x

          

4 (1)

Gender

    

x

x

        

x

 

x

x

      

x

 

23 (6)

Antenatal steroids

                     

x

    

4 (1)

Outborn

    

x

           

x

       

x

 

12 (3)

Apgar score

 

x

x

x

x

  

x

   

x

           

x

x

 

31 (8)

Surfactant use

       

x

        

x

    

x

    

12 (3)

Patent ductus arteriosus

      

x

  

x

  

x

  

x

          

15 (4)

Fluid intake day 7

            

x

             

4 (1)

Lowest blood pressure

                        

x

 

4 (1)

Lowest temperature

                        

x

 

4 (1)

Urine output

                        

x

 

4 (1)

Respiratory distress syndrome (RDS)

    

x

x

   

x

                

12 (3)

Severity of RDS

                       

x

  

4 (1)

Pneumonia

 

x

 

x

 

x

                    

12 (3)

Pulmonary hemorrhage

   

x

                      

4 (1)

Pulmonary interstitial emphysema

 

x

 

x

     

x

                

12 (3)

Sepsis

         

x

                

4 (1)

Seizures

 

x

                      

x

 

8 (2)

Intraventricular hemorrhage > grade II

     

x

   

x

                

8 (2)

Congenital malformation

                      

x

   

4 (1)

Postnatal age at mechanical ventilation

                

x

         

4 (1)

Ventilator settings

                           

Modality

           

x

     

x

      

x

x

15 (4)

Mean FiO2

         

x

x

x

    

x

x

       

x

23 (6)

Minimum FiO2

                      

x

   

4 (1)

Maximum FiO2

   

x

  

x

     

x

x

    

x

   

x

   

23 (6)

Duration FiO2 > 0.6

x

    

x

                    

8 (2)

FiO2 1.0 for > 24 hr

 

x

                        

4 (1)

Positive inspiratory pressure (PIP)

  

x

x

    

X

x

x

x

              

23 (6)

Duration PIP > 25cmH2O

     

x

                    

4 (1)

Rate

       

x

  

x

               

8 (2)

Intermittent mandatory ventilation (IMV)

      

x

 

X

x

             

x

  

15 (4)

IMV > 24 hrs or > 2d

x

              

x

     

x

    

8 (2)

Mean airway pressure

          

x

x

 

x

            

12 (3)

Ventilator index

       

x

                  

4 (1)

Laboratory

                           

pH

                        

x

 

4 (1)

pO2

   

x

                    

x

 

8 (2)

Oxygenation index

           

x

    

x

 

x

x

 

x

    

19 (5)

A-a DO2

                  

x

x

      

8 (2)

Pa/AO2

                  

x

 

x

     

8 (2)

Base excess

                      

x

x

  

8 (2)

  1. NA Not applicable; Un Unknown.