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Table 4 Distribution of DRD2/ANKK1 rs1800497 alleles and DRD4 exon III variable number of tandems repeat alleles in relation to BMI among all adult and pediatric subjects

From: Association analyses for dopamine receptor gene polymorphisms and weight status in a longitudinal analysis in obese children before and after lifestyle intervention

  Adults (lean)   Children (overweight or obese)  
  N (% of total) n = 583 Age Sex BMI N (% of total) n = 451 Age Sex BMI BMI-SDS
rs1800497          
  CC (A2/A2) 407 (69.8) 25.4 ± 4.5 161 M/246 F 19.2 ± 2.0 308 (68.3) 10.8 ± 2.6 139 M/169 F 27.5 ± 4.5 2.4 ± 0.5
  CT (A1/A2) 161 (27.6) 25.1 ± 4.3 64 M/97 F 19.1 ± 1.9 132 (29.3) 10.7 ± 2.7 60 M/72 F 27.2 ± 4.4 2.3 ± 0.5
  TT (A1/A1) 15 (2.6) 24.4 ± 3.0 6 M/9 F 18.2 ± 1.1 11 (2.4) 11.3 ± 1.7 4 M/7 F 26.5 ± 2.5 2.1 ± 0.4
DRD4 7R+         
  No 357 (61.2) 25.6 ± 4.6 149 M/208 F 19.2 ± 2.0 285 (63.2) 10.8 ± 2.6 135 M/150 F 27.2 ± 4.4 2.3 ± 0.5
  One 198 (34.0) 24.8 ± 4.1 71 M/127 F 19.0 ± 1.9 148 (32.8) 10.8 ± 2.7 62 M/86 F 27.4 ± 4.6 2.4 ± 0.5
  Two 28 (4.8) 25.4 ± 4.0 11 M/17 F 18.8 ± 1.5 18 (4.0) 11.4 ± 2.1 6 M/12 F 29.0 ± 3.8 2.5 ± 0.3
  1. Age and BMI values are Mean ± SD.