Table 4 Distribution of DRD2/ANKK1 rs1800497 alleles and DRD4 exon III variable number of tandems repeat alleles in relation to BMI among all adult and pediatric subjects
Adults (lean) | Children (overweight or obese) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
N (% of total) n = 583 | Age | Sex | BMI | N (% of total) n = 451 | Age | Sex | BMI | BMI-SDS | |
rs1800497 | |||||||||
CC (A2/A2) | 407 (69.8) | 25.4 ± 4.5 | 161 M/246 F | 19.2 ± 2.0 | 308 (68.3) | 10.8 ± 2.6 | 139 M/169 F | 27.5 ± 4.5 | 2.4 ± 0.5 |
CT (A1/A2) | 161 (27.6) | 25.1 ± 4.3 | 64 M/97 F | 19.1 ± 1.9 | 132 (29.3) | 10.7 ± 2.7 | 60 M/72 F | 27.2 ± 4.4 | 2.3 ± 0.5 |
TT (A1/A1) | 15 (2.6) | 24.4 ± 3.0 | 6 M/9 F | 18.2 ± 1.1 | 11 (2.4) | 11.3 ± 1.7 | 4 M/7 F | 26.5 ± 2.5 | 2.1 ± 0.4 |
DRD4 7R+ | |||||||||
No | 357 (61.2) | 25.6 ± 4.6 | 149 M/208 F | 19.2 ± 2.0 | 285 (63.2) | 10.8 ± 2.6 | 135 M/150 F | 27.2 ± 4.4 | 2.3 ± 0.5 |
One | 198 (34.0) | 24.8 ± 4.1 | 71 M/127 F | 19.0 ± 1.9 | 148 (32.8) | 10.8 ± 2.7 | 62 M/86 F | 27.4 ± 4.6 | 2.4 ± 0.5 |
Two | 28 (4.8) | 25.4 ± 4.0 | 11 M/17 F | 18.8 ± 1.5 | 18 (4.0) | 11.4 ± 2.1 | 6 M/12 F | 29.0 ± 3.8 | 2.5 ± 0.3 |