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Table 1 Clinical characteristics in 216 preterm infants with (Cases) or without (Controls) rectal bleeding

From: Risk factors of mild rectal bleeding in very low birth weight infants: a case control study

 

Controls n = 144

Cases n = 72

p*

Pregnancy and delivery

   

Singleton, n (%)

99 (68.8)

49 (68.05)

0.835

Antenatal steroids, n (%)

123 (85.4)

64 (88.9)

0.876

Hypertension, n (%)

14 (9.7)

16 (22.2)

0.03

Diabetes, n (%)

10 (6.9)

11 (15.3)

0.168

Cesarean section, n (%)

102 (73.6)

48 (66.7)

0.250

At birth

   

Birth weight (g)

1150 [500–1495]

1140 [540–1480]

0.831

Gestational age (weeks)

29 [24–32]

28 [24–32]

0.446

Birth weight < −2SD, n (%)

30 (20.8)

16 (22.2)

0.814

Drugs before rectal bleeding

   

Antiacids, n (%)

19 (13.1)

12 (16.7)

0.663

Ibuprofen, n (%)

19 (13.2)

22 (30.6)

0.003

Postnatal steroids, n (%)

4 (2.8)

6 (8.3)

0 .087

Respiratory support before rectal bleeding

   

Assisted ventilation (hours)

19 [0–1916]

23.5 [0–1311]

0.955

CPAP (hours)

124 [0–2411]

212 [0–9312]

0.178

Oxygen therapy (hours)

15 [0–2913]

39 [0–2720]

0.567

  1. Number of subjects (%) or median [min-max].
  2. *Chi-2 test (or Fisher’s exact test when required) and Wilcoxon test were performed to compare qualitative and quantitative value, respectively.