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Table 1 Clinical characteristics in 216 preterm infants with (Cases) or without (Controls) rectal bleeding

From: Risk factors of mild rectal bleeding in very low birth weight infants: a case control study

  Controls n = 144 Cases n = 72 p*
Pregnancy and delivery    
Singleton, n (%) 99 (68.8) 49 (68.05) 0.835
Antenatal steroids, n (%) 123 (85.4) 64 (88.9) 0.876
Hypertension, n (%) 14 (9.7) 16 (22.2) 0.03
Diabetes, n (%) 10 (6.9) 11 (15.3) 0.168
Cesarean section, n (%) 102 (73.6) 48 (66.7) 0.250
At birth    
Birth weight (g) 1150 [500–1495] 1140 [540–1480] 0.831
Gestational age (weeks) 29 [24–32] 28 [24–32] 0.446
Birth weight < −2SD, n (%) 30 (20.8) 16 (22.2) 0.814
Drugs before rectal bleeding    
Antiacids, n (%) 19 (13.1) 12 (16.7) 0.663
Ibuprofen, n (%) 19 (13.2) 22 (30.6) 0.003
Postnatal steroids, n (%) 4 (2.8) 6 (8.3) 0 .087
Respiratory support before rectal bleeding    
Assisted ventilation (hours) 19 [0–1916] 23.5 [0–1311] 0.955
CPAP (hours) 124 [0–2411] 212 [0–9312] 0.178
Oxygen therapy (hours) 15 [0–2913] 39 [0–2720] 0.567
  1. Number of subjects (%) or median [min-max].
  2. *Chi-2 test (or Fisher’s exact test when required) and Wilcoxon test were performed to compare qualitative and quantitative value, respectively.