Table 3 Formulae supplemented with B lactis
Outcome | RCTs | Participants | Effect estimate |
|---|---|---|---|
MD (95% CI), fixed effect model | |||
Weight gain (g/day) | 4 | 266 | 0.96 (−0.70 to 2.63) (random) |
• Reduced protein (1.8 g/100 kcal) IF | 1 | 56 | 1.40 (−1.73 to 4.52) (random) |
• Reduced protein (1.8 g/100 kcal) IF with LCPUFA | 1 | 98 | 1.71 (−0.7 to 4.12) (random) |
• Reduced protein (1.9 g/100 kcal) pHF | 1 | 55 | −1.83 (−5.35 to 1.69) (random) |
• Acidified formula (2 g protein/100 kcal) | 1 | 57 | 3.24 (−0.18 to 6.66) (random) |
Length (mm/month) | 4 | 261 | −0.39 (−1.32 to 0.53) |
• Reduced protein (1.8 g/100 kcal) IF | 1 | 56 | 1.28 (−1.28 to 3.83) |
• Reduced protein (1.8 g/100 kcal) IF with LCPUFA | 1 | 93 | −0.60 (−2.39 to 1.18) |
• Reduced protein (1.9 g/100 kcal) pHF | 1 | 55 | −0.83 (−2.27 to 0.60) |
• Acidified IF (2 g protein/100 kcal) | 1 | 57 | −0.27 (−2.42 to 1.89) |
Head circumference (mm/month) | 3 | 207 | 0.56 (−0.17 to 1.30) |
• Reduced protein (1.8 g/100 kcal) IF | 1 | 56 | 0.36 (−0.79 to 1.51) |
• Reduced protein (1.8 g/100 kcal) IF with LCPUFA | 1 | 95 | 0.27 (−0.91 to 1.45) |
• Acidified IF (2 g protein/100 kcal) | 1 | 56 | 1.51 (−0.09 to 3.11) |
Body mass index (BMI)(kg/m 2 /month) | 3 | 206 | 0.09 (−0.05 to 0.22) |
• Reduced protein (1.8 g/100 kcal) IF | 1 | 56 | −0.01 (−0.25 to 0.24) |
• Reduced protein (1.8 g/100 kcal) IF with LCPUFA | 1 | 93 | 0.10 (−0.10 to 0.30) |
• Acidified IF (2 g protein/100 kcal) | 1 | 57 | 0.17 (−0.10 to 0.43) |
Final weight percentiles (IF 2.2 g protein/100 kcal) | 1 | 39 | −2.7 (−13.37 to 7.97) |
Final length percentiles (IF 2.2 g protein/100 kcal) | 1 | 39 | −2.00 (−12.75 to 8.75) |
Final HC percentiles (IF 2.2 g protein/100 kcal) | 1 | 39 | −7.5 (−18.15 to 3.15) |