Table 3 Predictors of HIV seropositivity in study population and their sensitivity and specificity
Clinical variable | Sensitivity% (95% CI) | Specificity% (95% CI) | PPV% (95% CI) | NPV% (95% CI) |
|---|---|---|---|---|
Prolonged diarrhoea | 23.9 (14.3 - 35.9) | 94.4 ( 90.0-97.3) | 61.5 (40.6 - 79.8) | 76.8 (70.7 - 82.2) |
Chronic cough | 40.3 (28.5 - 53.0) | 95.5 (91.4 - 98.1) | 77.1 (59.9 - 89.6) | 81.0 (75.1 - 86.1) |
Prolonged fever | 46.3 (34.0 - 58.9) | 92.2 (87.2 - 95.7) | 68.9 (53.4 - 81.8) | 82.1 (76.1 - 87.1) |
Oral thrush | 68.7 (56.2-79.4) | 82.1 (75.7-87.4) | 59.0 (47.3-70.0) | 87.5 (81.5-92.1) |
Generalised lymphadenopathy | 44.8 (32.6-57.4) | 98.3 (95.2-99.7) | 90.9 (75.7-98.1) | 82.6 (76.9-87.5) |
Sensitivities and specificities of a clinical algorithm consisting of above variables | ||||
No of parameters identified | Sensitivity% | Specificity% | Correctly Classified% | |
≥ 1 | 92.5 | 72.1 | 77.6 | |
≥ 2 | 68.7 | 92.2 | 85.8 | |
≥ 3 | 41.7 | 98.3 | 82.9 | |
≥ 4 | 16.4 | 100.0 | 77.2 | |
5 | 4.8 | 100.0 | 74.0 | |