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Table 2 Normal values of diagnostic markers in study

From: Neutrophil counts distinguish between malignancy and arthritis in children with musculoskeletal pain: a case–control study

Diagnostic markers

Normal value (reference value)

Neoplasia (N=63)

JIA (N=71)

Lower values or presence (n/N; %)

Normal values (n/N; %)

Higher values or positivity (n/N; %)

Lower values or present (n/N; %)

Normal values (n/N; %)

Higher values or positivity (n/N; %)

WBC count

4-10 × 109/L

11/60; 18.3%

27/60; 45%

22/60; 36.7%

3/68; 4.4%

35/68; 51.5%

30/68; 44.1%

Neutrophil count

1 × 109/L

25/55; 45.5%

30/55; 54.5%

0/55; 0%

2/61; 3.3%

59/61; 96.7%

0/61; 0%

Platelet count

150-300 × 109/L

34/60; 56.7%

13/60; 21.7%

13/60; 21.7%

2/68; 2.9%

17/68; 25%

49/68; 72.1%

Hemoglobin (Hgb)

≥10 gr/dl

34/60; 56.7%

26/60; 43.3%

NA

62/68; 91.2%

6/68; 8.8%

NA

Lactic dehydrogenase (LDH)

<500 IU/L

NA

7/58; 12.1%

51/58; 87.9%

NA

16/49; 32.7%

33/49; 67.3%

Erythrocyte sedimentation rate (ESR)

<20 mm/h

NA

4/37; 10.8%

33/37; 89.2%

NA

14/68; 20.6%

54/68; 79.4%

C-reactive protein (CRP)

<1 mg/dl

NA

13/52; 25%

39/52; 75%

NA

14/61; 23%

47/61; 77%

Antinuclear antibody (ANA)

≥1:80

NA

16/19; 84.2%

3/19; 15.8%

NA

30/62; 48.4%

32/62; 51.6%

IgG

751–1560 mg/dl

9/51; 17.6%

35/51; 68.6%

7/51; 13.7%

2/57; 3.5%

35/57; 61.4%

20/57; 35.1%

IgM

46–304 mg/dl

4/51; 7.8%

47/51; 92.2%

0/51; 0%

1/57; 1.8%

53/57; 93%

3/57; 5.3%

IgA

82–453 mg/dl

17/51; 33.3%

33/51; 64.7%

1/51; 2%

6/57; 10.5%

49/57; 86%

2/57; 3.5%

C3

79–152 mg/dl

1/36; 2.8%

14/36; 38.9%

21/36; 58.3%

3/54; 5.6%

29/54; 53.7%

22/54; 40.7%

C4

16–38 mg/dl

1/36; 2.8%

19/36; 52.8%

16/36; 44.4%

4/53; 7.5%

44/53; 83%

5/53; 9.4%

Anti-EBV IgM

Negative

NA

37/44; 84.1%

7/44; 15.9%

NA

13/14; 92.9%

1/14; 7.1%

Anti-EBV IgG

Negative

NA

11/44; 25%

33/44; 75%

NA

7/15; 46.7%

8/15; 53.3%

Anti-EA EBV IgG

Negative

NA

21/35; 60%

14/35; 40%

NA

10/10; 100%

0/10; 0%

Anti-CMV IgM

Negative

NA

32/34; 94.1%

2/34; 5.9%

NA

8/10; 80%

2/10; 20%

Anti-CMV IgG

Negative

NA

9/33; 27.3%

24/33; 72.7%

NA

8/10; 80%

2/10; 20%