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Table 4 Comparison of healthcare utilization and cost estimates (unadjusted) for medical, surgical NEC and matched control groups from 6 months to 3 years of age

From: Long term healthcare costs of infants who survived neonatal necrotizing enterocolitis: a retrospective longitudinal study among infants enrolled in Texas Medicaid

Age ->

6-12 months

12-24 months

24-36 months

 

Controls

Medical NEC

Surgical NEC

Controls

Medical NEC

Surgical NEC

Controls

Medical NEC

Surgical NEC

N ->

2109

141

62

1326

102

42

951

70

35

Mean Hospital

0.1 (0.4)

0.2 (1)**

1 (1)**

0 (1)

0 (0.5)

1 (2)**

0 (1)

0 (0.3)

1 (1)**

admissions a (SD)

IQR

0

0

1

0

0

1

0

0

1

90th percentile

0

1

2

1

1

3

0

0

1

Mean Hospital days b (SD)

1 (9)

4 (17)**

16 (33)**

1 (4)

1 (4)

10 (33)**

0.5 (3)

0.5 (3)

2 (6)**

IQR

0

0

10

0

0

4

0

0

2

90th percentile

2

6

59

2

3

13

0

0

3

Inpatient costs (SD) b

2,922 (28,056)

8,068 (33,452)

35,867 (79,511)**

1,942 (12,319)

2,557 (9,823)

23,102 (71,101)**

1,046 (8,737)

1,039 (6,395)

7,842 (29,930)**

IQR

0

0

24,150

0

0

7,589

0

0

2,615

90th percentile

2,167

8,769

126,901

3,435

6,296

26,085

0

0

11,786

Total home healthcare

741 (5,575)

2,882 (14,251)**

3,564 (9,895)**

2,539 (17,372)

3,102 (16,412)

11,364 (34,901)**

2,237 (14,806)

2,380 (13,167)

9,485 (23,184)**

b costs (SD)

IQR

0

0

1,741

0

0

3,533

0

0

4,947

90th percentile

160

1,536

7,761

184

386

36,309

199

128

31,976

Total ambulatory care

2,332 (7,388)

5,129 (16,391)**

8,764 (14,920)**

5,961 (21,091)

6,392 (18,719)

21,715 (38,769)**

4,346 (19,294)

3,946 (14,009)

16,461 (34,291)**

costs b,c (SD)

IQR

1,247

3,414

10,572

2,154

4,144

21,573

1,372

1,874

11,320

90th percentile

5,958

10,846

20,126

14,984

17,382

61,962

5,691

4,357

61,559

Overall healthcare

5,598(30,654)

13,610 (38,264)**

45,213 (87,497)**

8,726 (28,039)

9,856 (23,111)

46,378 (91,535)**

6,279 (24,018)

5,809 (16,966)

26,055 (52,637)**

IQR

2,238

7,157

41,957

3,987

8,921

32,077

2,466

1,706

17,753

90th percentile

8,661

25,432

143,132

18,075

22,827

106,997

8,779

10,290

84,338

  1. SD standard deviation, IQR interquartile range (difference between the 75th and 25th percentile estimates).
  2. *p<0.05 and **p<0.01.
  3. a) Outcome was assumed to be negative binomial distributed while evaluating statistical significance of difference estimates between NEC versus control groups. b) Outcome was assumed to be t-distributed while evaluating statistical significance of difference estimates between NEC versus control groups. c) Total ambulatory care costs included costs of laboratory, medical consultation, preventive care, ambulatory surgery, home health services and professional payments. Overall healthcare costs include inpatient, ambulatory as well as prescription medication costs.