Table 5 Fixed effects model data and analyses

Overweight/Obesity

1.1 Overweight vs. physician-diagnosed asthma at age 9+ (Total)

3

12237

Risk ratio (IV, Fixed, 95% CI)

1.35 [1.15, 1.58]

1.2 Obese vs. physician-diagnosed asthma in children ages 8–18 years (Total)

2

15688

Risk ratio (IV, Fixed, 95% CI)

1.50 [1.22, 1.83]

1.3 Overweight vs. physician-diagnosed asthma at age 9+ (Boys)

3

6180

Risk ratio (IV, Fixed, 95% CI)

1.41 [1.05, 1.88]

1.4 Overweight vs. physician-diagnosed asthma at age 9+ (Girls)

3

6057

Risk ratio (IV, Fixed, 95% CI)

1.19 [0.91, 1.56]

1.5 Obese vs. physician-diagnosed asthma in children ages 8–18 years (Boys)

2

4005

Risk ratio (IV, Fixed, 95% CI)

1.40 [1.01, 1.93]

1.6 Obese vs. physician-diagnosed asthma in children ages 8–18 years (Girls)

2

3839

Risk ratio (IV, Fixed, 95% CI)

1.53 [1.09, 2.14]

1.7 BMI at age 3 vs. incident asthma at 6 years of age

1

249

Odds ratio (IV, Fixed, 95% CI)

1.04 [0.50, 2.16]

1.8 BMI at age 3 vs. incident asthma at 8 years of age

1

229

Odds ratio (IV, Fixed, 95% CI)

1.51 [0.69, 3.30]

1.9 BMI at age 5 vs. incident asthma at 6 years of age

1

255

Odds ratio (IV, Fixed, 95% CI)

0.91 [0.45, 1.84]

1.10 BMI at age 5 vs. incident asthma at 8 years of age

1

235

Odds ratio (IV, Fixed, 95% CI)

1.31 [0.61, 2.81]

BMI Z-score

2.1 BMI Z-score vs. any physician diagnosed asthma (Total)

2

25280

Risk ratio (IV, Fixed, 95% CI)

1.03 (0.97, 1.10)

2.2 BMI Z-score vs. any physician diagnosed asthma (Boys)

2

6442

Risk ratio (IV, Fixed, 95% CI)

0.92 [0.81, 1.04]

2.3 BMI Z-score vs. any physician diagnosed asthma (Girls)

2

6198

Risk ratio (IV, Fixed, 95% CI)

1.19 [1.06, 1.34]

2.4 Asthma at age 14 years (Total)

1

2812

Odds ratio (IV, Fixed, 95% CI)

1.01 [0.92, 1.11]

2.5 Asthma at age 14 years (Boys)

1

1472

Odds ratio (IV, Fixed, 95% CI)

0.87 [0.75, 1.01]

2.6 Asthma at age 14 years (Girls)

1

1340

Odds ratio (IV, Fixed, 95% CI)

1.14 [1.00, 1.30]

BMI Z-score

3.1 BMI at entry vs. asthma with any wheeze (Boys)

1

4970

Risk ratio (IV, Fixed, 95% CI)

1.05 [0.83, 1.33]

3.2 BMI at entry vs. asthma with any wheeze (Girls)

1

4858

Risk ratio (IV, Fixed, 95% CI)

1.43 [1.09, 1.88]