Table 3 Reporting of methodological characteristics of pediatric RCTs
Items | Quantity |
|---|---|
(n, %) | |
Method of random sequence generation | |
Low risk | 161 (14.9%) |
Random number table | 121 (11.2%) |
Drawing of lots | 28 (2.6%) |
Computer | 9 (0.8%) |
Lottery | 1 (0.1%) |
Coin toss | 1 (0.1%) |
Dice | 1 (0.1%) |
High risk | |
Visiting sequence of inpatient/outpatient, the card number of inpatient/outpatient number and birth date. | 113 (10.5%) |
Unclear | 803 (74.6%) |
Method of allocation concealment | |
Low risk | 10 (1%) |
Central allocation | 7 (0.7%) |
Sealed opaque envelopes | 3 (0.3%) |
High risk | -- |
Unclear | 1067 (99%) |
Blinding | |
Low risk | 6 (0.6%) |
Single blind (participants) | 3 (0.3%) |
Double blind (participants and investigators) | 2 (0.2%) |
Triple blind (participants, investigators, outcome assessors) | 1 (0.1%) |
High risk | -- |
Unclear | 1071 (99.4%) |
Incomplete outcome data | |
Low risk | 988 (91.7%) |
High risk | -- |
Unclear | 89 (8.3%) |
Selective reporting | |
Low risk | -- |
High risk | 18 (1.7%) |
Unclear | 1059 (98.3%) |
Other bias | |
Low risk | -- |
High risk | 2 (0.2%) |
Unclear | 1075 (99.8%) |