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Table 3 Reporting of methodological characteristics of pediatric RCTs

From: 10-year trend in quantity and quality of pediatric randomized controlled trials published in mainland China: 2002–2011

Items Quantity
  (n, %)
Method of random sequence generation  
Low risk 161 (14.9%)
  Random number table 121 (11.2%)
  Drawing of lots 28 (2.6%)
  Computer 9 (0.8%)
  Lottery 1 (0.1%)
  Coin toss 1 (0.1%)
  Dice 1 (0.1%)
High risk  
  Visiting sequence of inpatient/outpatient, the card number of inpatient/outpatient number and birth date. 113 (10.5%)
Unclear 803 (74.6%)
Method of allocation concealment  
Low risk 10 (1%)
  Central allocation 7 (0.7%)
  Sealed opaque envelopes 3 (0.3%)
High risk --
Unclear 1067 (99%)
Blinding  
Low risk 6 (0.6%)
 Single blind (participants) 3 (0.3%)
  Double blind (participants and investigators) 2 (0.2%)
  Triple blind (participants, investigators, outcome assessors) 1 (0.1%)
High risk --
Unclear 1071 (99.4%)
Incomplete outcome data  
Low risk 988 (91.7%)
High risk --
Unclear 89 (8.3%)
Selective reporting  
Low risk --
High risk 18 (1.7%)
Unclear 1059 (98.3%)
Other bias  
Low risk --
High risk 2 (0.2%)
Unclear 1075 (99.8%)
  1. -- means no data available.