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Table 4 Effects of iron supplementation on growth and neurodevelopment in low birth weight infants

From: Benefits of Iron supplementation for low birth weight infants: A systematic review

Study

Anthropometric Data

Neurodevelopmental Outcome

Hall et al. 1993[25]

No differences in growth rate, length, head circumference

NA

Friel et al. 2001[28]

No differences in WTZ, HTZ at 12 months of age

No difference in GDA; no infant had abnormal development

Steinmacher et al. 2007[32]

NA

More infants in the late iron suppl. group had abnormal neurologic examination; no differences in cognitive development, mobility, hearing, vision, growth; late vs early iron suppl. was not an risk factor for abnormal neurologic examination, disability, or cognitive impairment

Aggarwal et al. 2005[29]

No differences in weight, length, head circumference

NA

Sankar et al. 2009[34]

No difference in weight

NA

Berglund et al. 2010[35]

No differences in weight, length, head circumference

NA

  1. GDA, Griffiths’ Development Assessment; HTZ, height for age z score; suppl., supplement; WTZ, weight for age z score; NA, not available.