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Table 3 Immunologic response to antiretroviral therapy among HIV-1-infected children

From: Treatment outcomes among HIV-1 and HIV-2 infected children initiating antiretroviral therapy in a concentrated low prevalence setting in West Africa

Increase in CD4% from baseline following initiation of ART in all children (n = 65)

Duration of follow-up (months)

Number of childrena

Median CD4% (IQR)

Median CD4% increase from baseline (IQR)

P b

6

42

23.3% (18.0 – 28.5)

11% (4 – 15)

< 0.001

12

37

27% (20 – 34)

15% (7 – 20)

< 0.001

18

30

27.5% (16 – 36)

17% (6 – 22)

< 0.001

24

25

29% (21 – 38)

18.5% (5 – 22)

0.0001

30

19

32% (19 – 38)

15% (9 – 24)

0.0001

36

12

30.3% (22.5 – 39.5)

18.5% (10.8 – 24.5)

0.002

  1. a Number of children tested at corresponding length of follow-up. Attrition in numbers is attributable to lack of data, loss to follow-up or death.
  2. b Wilcoxon signed ranks test.