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Table 2 Demographic, laboratory and clinical summary of HIV-2 infected children on antiretroviral therapy

From: Treatment outcomes among HIV-1 and HIV-2 infected children initiating antiretroviral therapy in a concentrated low prevalence setting in West Africa

Patient

Sex

Age at diagnosis (years)

Parents status

Age at start of ART (years)

Baseline CD4+count (%CD4)

Baseline Viral load (log10copies/ml)

Remarks

1

F

11

Both parents alive; HIV status unknown

12

40 (1%)

Nil

WHO stage 4 at start of ART Clinical follow-up for 2 months No follow-up laboratory data; Died

2

M

8

Mother dead (HIV-2 positive), Father alive (HIV-negative)

14

280 (27%)

4.5

WHO stage 4 at start of ART Clinical follow-up for 38 months Sub-optimal CD4 recovery; >0.5 log10 increase in viral load at 12 weeks; did not achieve virologic suppression throughout follow-up; LTFU

4

F

2

Both parents HIV-2 positive and alive (both on ART)

4

570 (13%)

4.6

WHO stage 3 at start of ART Clinical follow-up for 10 months No CD4 cell gain; ART discontinued at 29 weeks due to poor adherence; No follow-up viral load data; LTFU

5

M

6

Mother dead, father unknown; both parents HIV status unknown

6

140 (4%)

3.1

WHO stage 3 at start of ART Clinical follow-up for 4 months No follow-up laboratory data; Died

6

M

12

Mother dead, father unknown; both parents HIV status unknown

12

110 (8%)

4.9

WHO stage 2 at start of ART Clinical follow-up for 3 months Achieved an increase in CD4 count of 50 cells/mm3 but a 1.0 log10 increase in viral load at 12 weeks; LTFU

  1. NOTE. LTFU = Lost to follow-up; EPTB = Extra pulmonary tuberculosis; PTB = Pulmonary tuberculosis.