From: Birth-weight, insulin levels, and HOMA-IR in newborns at term
Overall population | SGA | AGA | LGA | |||
---|---|---|---|---|---|---|
n = 107 | n = 13 | n = 72 | n = 22 | F | p | |
Family history of diabetes, n (%) | 45 (40.1) | 8 (61.5) | 26 (36.1) | 11 (50.0) | - | 0.13 |
Parity | 2.2 ± 1.0 | 2.3 ± 1.2 | 2.0 ± 1.0 | 2.4 ± 1.0 | 0.94 | 0.39 |
Mother’s age, years | 25.0 ± 5.0 | 23.0 ± 6.1 | 24.8 ± 5.2 | 26.6 ± 3.9 | 2.14 | 0.12 |
Weight before pregnancy, kg | 61.8 ± 11.7 | 55.9 ± 11.8 | 61.1 ± 10.6 | 67.5 ± 13.2 | 4.60 | 0.01*, **,† |
Weight gain through pregnancy, kg | 13.0 ± 5.2 | 11.1 ± 6.7 | 12.8 ± 5.3 | 14.7 ± 3.2 | 1.95 | 0.14 |
Body mass index before pregnancy, k/m2 | 24.1 ± 4.6 | 22.1 ± 5.1 | 23.9 ± 4.0 | 25.8 ± 5.5 | 2.8 | 0.06 |
Gestational age, weeks | 39.1 ± 1.8 | 39.0 ± 0.8 | 39.3 ± 1.2 | 39.8 ± 0.9 | 2.22 | 0.11 |
Newborn’s birth weight, g | 3312 ± 678 | 2083 ± 356 | 3270 ± 380 | 4175 ± 197 | 149.3 | <0.001*,**,†,‡,§ |
Newborn’s plasma glucose at birth, mmol/L | 5.9 ± 2.7 | 7.2 ± 5.5 | 5.8 ± 2.0 | 5.2 ± 2.2 | 2.15 | 0.15 |
Newborn’s insulin at birth, μU/mL | 7.1 ± 4.3 | 6.7 ± 4.5 | 6.3 ± 3.7 | 9.6 ± 4.9 | 5.32 | 0.001‡ |
HOMA-IR index | 1.9 ± 1.5 | 1.9 ± 1.4 | 1.7 ± 1.3 | 2.3 ± 1.5 | 1.63 | 0.04‡ |