Table 7 Review of the literature on nasal intermittent positive pressure ventilation (NIPPV) vs. nasal continuous positive airway pressure (NCPAP) for preventing extubation failure
Study author, Year | Inclusion criteria | Intervention group | Control group | Primary outcome | Results |
|---|---|---|---|---|---|
Barrington 2001 | BW < 1,251 grams PNA < 6 wks | NSIMV (N = 27) | NCPAP (N = 27) | Extubation failure at 72 hours | 4/27 (14%) vs. 12/27 (44%) in the NSIMV vs. NCPAP (P < 0.05) Median age at extubation (range) 3 (1, 29) vs. 3 (1, 40) days |
Friedlich 1999 | BW 500-1,500 grams | NP-SIMV (N = 22) | NCPAP (N = 19) | Respiratory failure at 48 hours | 1/22 (5%) vs.7/19 (37%) in the NP-SIMV vs. NCPAP group (P = 0.016) Median age at extubation (range) 18.5 (1, 120) vs. 21(1, 54) days |
Khalaf 2001 | GA ≤ 34 weeks, RDS | SNIPPV (N = 34) | NCPAP (N = 30) | Remained extubated at 72 hours | 32/34 (94%) vs. 18/30 (60%) in the SNIPPV vs. NCPAP group (P < 0.01) Median age at extubation (range) 4 (1, 83) vs. 2.5 (1, 106) days |
Morretti 2008 | BW < 1,251 grams PNA < 14 days | NFSIPPV (N = 32) | NCPAP (N = 31) | Remained extubated at 72 hours | 30/32 (94%) vs. 19/31(61%) in the NFSIPPV vs. NCPAP (P < 0.01) Median age at extubation (range) 4 (1, 14) vs. 6 (1, 14) days |