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Table 4 Association of G/A + A/A genotypes of -844 PAI-1 polymorphism with obesity and lipid levels

From: Relationship of metabolic syndrome and its components with -844 G/A and HindIII C/G PAI-1 gene polymorphisms in Mexican children

-844 PAI-1
Genotypes
Obesity OR (95% CI) P*
value
  < 95th percentile % (n= 58) ≥ 95th percentile % (n= 42)    
G/G § 64 (34) 40 (19) 1   
G/A + A/A 36 (19) 60 (28) 2.6 1.17-5.92 0.01
  Plasma triglycerides levels    
  < 150 mg/dL % ( n = 61) > 150 mg/dL % ( n = 39)    
G/G § 62 (38) 38 (15) 1   
G/A + A/A 38 (23) 62 (24) 2.6 1.16-6.04 0.02
  Plasma HDL-cholesterol levels    
  > 40 mg/dL % ( n = 58) < 40 mg/dL % ( n = 42)    
G/G § 68 (36) 32 (17) 1   
G/A + A/A 47 (22) 53 (25) 2.4 1.06-5.42 0.03
  1. *Chi square test, § Reference category, OR = odds ratio, CI = confidence interval