Table 4 Association of G/A + A/A genotypes of -844 PAI-1 polymorphism with obesity and lipid levels
-844 PAI-1 Genotypes | Obesity | OR | (95% CI) | P* value | |
|---|---|---|---|---|---|
< 95th percentile % (n= 58) | ≥ 95th percentile % (n= 42) | ||||
G/G § | 64 (34) | 40 (19) | 1 | ||
G/A + A/A | 36 (19) | 60 (28) | 2.6 | 1.17-5.92 | 0.01 |
Plasma triglycerides levels | |||||
< 150 mg/dL % ( n = 61) | > 150 mg/dL % ( n = 39) | ||||
G/G § | 62 (38) | 38 (15) | 1 | ||
G/A + A/A | 38 (23) | 62 (24) | 2.6 | 1.16-6.04 | 0.02 |
Plasma HDL-cholesterol levels | |||||
> 40 mg/dL % ( n = 58) | < 40 mg/dL % ( n = 42) | ||||
G/G § | 68 (36) | 32 (17) | 1 | ||
G/A + A/A | 47 (22) | 53 (25) | 2.4 | 1.06-5.42 | 0.03 |