Table 3 General characteristics according PAI-1 polymorphism following a dominant genetic model
-844 G/A PAI-1 | HindIIIC/G PAI-1 | |||||
|---|---|---|---|---|---|---|
Variables | G/G n= 53 | G/A + A/A n= 47 | Pvalue | C/C n= 57 | C/G + G/G n= 43 | Pvalue |
Age (years) c | 9 (6-11) | 9 (6-11) | 0.22 | 9 (6-11) | 9 (6-11) | 0.08 |
Gender (%) a | 0.30 | 0.06 | ||||
Male | 28 (53) | 20 (43) | 32 (56) | 16 (37) | ||
Female | 25 (47) | 27 (57) | 25 (44) | 27 (63) | ||
BMI (kg/m 2 ) c | 17 (13.7-26.6) | 20 (15.1-27.5) | 0.09 | 18 (14-29) | 20 (15-26) | 0.67 |
Obesity (%) | 0.01 | 0.25 | ||||
Yes | 19 (36) | 28 (60) | 24 (42) | 23 (53) | ||
No | 34 (64) | 19 (40) | 33 (58) | 20 (47) | ||
Circumferences | ||||||
Waist (cm) c | 66 (54-87) | 69 (57-89) | 0.22 | 67 (54-90) | 66 (57-88) | 0.84 |
Arm (cm) c | 20 (16-28) | 22 (17-29) | 0.04 | 21 (16-30) | 21 (17-28) | 0.68 |
Skinfolds | ||||||
Biceps (mm) b | 15 ± 4.32 | 16 ± 4.70 | 0.05 | 15 ± 4.2 | 16 ± 4.9 | 0.27 |
Triceps (mm) c | 13 (9-22) | 16 (10-20.5) | 0.01 | 14 (9.5-21.5) | 15 (9-22) | 0.75 |
Subscapular (mm) c | 13 (5.5-22) | 15 (8.5-22) | 0.03 | 14 (6-25) | 13 (6-22) | 0.85 |
Biochemical measurements | ||||||
Glucose (mg/dL) c | 95 (72-116) | 96 (72-112) | 0.38 | 95 (72-110) | 95 (72-112) | 0.59 |
Total cholesterol (mg/dL) b | 168 ± 27.91 | 175 ± 31.05 | 0.20 | 165 ± 29.6 | 179 ± 28 | 0.02 |
Triglycerides (mg/dL) c | 86 (38-225) | 150 (36-200) | 0.09 | 91 (29-200) | 116 (38-204) | 0.13 |
HDL-C (mg/dL) c | 53 (25-102) | 39 (23-89) | 0.04 | 49 (21-99) | 40 (25-98) | 0.54 |
Insulin (μU/mL) c | 5 (0.09-27.5) | 10 (1.25-22.7) | 0.10 | 7 (0.7-25) | 7 (0.5-23) | 0.91 |
HOMA c | 0.5 (0-6.04) | 1 (0-5.5) | 0.30 | 1.62 (0.1-6.0) | 1.8 (0.1-6.0) | 0.89 |
Insulin resistance a | 0.19 | 0.78 | ||||
Si | 9 (17) | 13 (28) | 12 (29) | 10 (32) | ||
No | 44 (83) | 34 (72) | 29 (71) | 21 (68) | ||