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Table 1 Genotype and allele frequencies of -844 and HindIII PAI-1 polymorphisms in cases and controls

From: Relationship of metabolic syndrome and its components with -844 G/A and HindIII C/G PAI-1 gene polymorphisms in Mexican children

Polymorphism Metabolic
syndrome
% (n= 48)
Metabolically
healthy
% (n = 52)
P value* OR CI (95%); Pvalue
-844 G/A PAI-1     
Genotype     
G/G § 40 (19) 65 (34) 0.034 1.0
G/A 52 (25) 31 (16)   2.8 (1.11-7.08); 0.015
A/A 8 (4) 4 (2)   3.6 (0.45-42.06); 0.15
Allele     
G 66 (63) 81 (84) 0.015 1.0
A 34 (33) 19 (20)   2.2 (1.10-4.43); 0.015
Genetic model     
Do     
G/G § 40 (19) 65 (34) 0.01 1.0
G/A + A/A 60 (29) 35 (18)   2.9 (1.18-7.05); 0.009
HindIII C/G PAI-1     
Genotype     
C/C § 50 (24) 63 (33) 0.28 1.0
C/G 44 (21) 35 (18)   1.6 (0.65-3.95); 0.25
G/G 6 (3) 2 (1)   4.12 (0.30-222.9); 0.22
Allele     
C 72 (69) 81 (84) 0.13 1.0
G 28 (27) 19 (20)   1.64 (0.8-3.36); 0.13
Genetic model     
Do     
C/C § 50 (24) 63 (33) 0.17 1.0
C/G + G/G 50 (24) 37 (19)   1.73 (0.75-4.17); 0.13
  1. *Chi square test χ 2; OR = odds ratio; CI = confidence interval; Do = dominant model
  2. §Reference category