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Table 1 Population characteristics of childhood cancer survivors (CCS) compared to controls

From: Modifiable risk factors associated with bone deficits in childhood cancer survivors

  

CCS(n = 319)

Controls(n = 208)

 
  

Mean ± SE

Mean ± SE

P

Age at Study, years

14.5 ± 0.1

13.7 ± 0.2

< 0.001

Height, Z-score

0.1 ± 0.1

0.4 ± 0.1

< 0.001

Weight, Z-score

0.5 ± 0.1

0.6 ± 0.1

0.363

% Body Fat†

28.1 ± 0.8

25.9 ± 0.9

0.007

Fat Mass, kg†

16.5 ± 0.7

14.8 ± 0.8

0.024

Lean Body Mass, kg†

38.5 ± 0.5

39.8 ± 0.6

0.015

IGF-1 SDS

-1.24 ± 0.05

-1.04 ± 0.06

0.004

IL-6, pg/ml†

1.4 ± 0.1

1.6 ± 0.3

0.505

Bone Age, years

14.5 ± 0.1

13.8 ± 0.2

< 0.001

Relative Bone Age

1.01 ± 0.01

1.01 ± 0.01

0.425

Tanner Score

3.6 ± 0.1

3.3 ± 0.1

0.068

Calcium Intake, mg/day

1280 ± 30

1257 ± 38

0.575

Vitamin D Intake, IU/day

331 ± 10

330 ± 12

0.968

Physical Activity Score, MET - minutes per week

58.6 ± 3.8

65.9 ± 4.9

0.191

  

N (Percent)

N (Percent)

 

Screen time

> 1 hr/day

225 (75.5)

147 (73.9)

0.680

 

0-1 hr/day

73 (24.5)

52 (26.1)

 

Ethnicity

White/not Hispanic

274 (85.9)

194 (93.3)

< 0.001

 

Others

45 (14.1)

14 (6.7)

 

Sex

Males

171 (53.6)

111 (53.4)

0.956

 

Females

148(46.4)

97 (46.6)

 

BMI

< 5%

9 (2.8)

4 (1.9)

0.495

 

≥ 5% to < 85%

210 (65.8)

137 (65.9)

0.995

 

≥ 85% to < 95%

42 (13.2)

43 (20.7)

0.031

 

≥ 95%

58 (18.2)

24 (11.5)

0.028

  1. †Adjusted for age, sex, ethnicity, and pubertal Tanner stage
  2. Relative Bone age = Bone age/actual age; MET = metabolic equivalent