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Table 2 Adjusted regression model results

From: Similar DNA methylation levels in specific imprinting control regions in children conceived with and without assisted reproductive technology: a cross-sectional study

Gene region of interest

ART group

SC group

Difference

Estimatec

95% CI

p-value

 

Na

Meanb

Na

Meanb

   

Lymphocyte samples

       

KvDMR

52

47.61

27

47.53

0.72

(-1.00, 2.45)

0.41

H19 CTCF3

53

42.16

27

41.70

0.66

(-0.94, 2.25)

0.42

H19 CTCF6

52

38.07

27

35.15

0.93

(-1.79, 3.65)

0.50

IGF2DMR0

53

50.04

26

48.32

0.08

(-1.82, 1.98)

0.94

IGF2R

52

69.26

27

72.13

-4.41

(-9.49, 0.66)

0.09

Buccal samples

       

KvDMR

64

53.46

29

52.60

1.60

(-2.77, 5.98)

0.47

H19 CTCF3

65

42.94

29

43.09

-0.24

(-2.96, 2.48)

0.86

H19 CTCF6

65

38.37

28

37.48

1.38

(-2.89, 5.64)

0.53

IGF2DMR0

65

36.52

27

35.03

2.07

(-0.28, 4.42)

0.08

IGF2R

65

79.45

29

81.35

-2.79

(-5.74, 0.16)

0.06

  1. a Number of subjects included in the analysis
  2. b The reported mean is averaged over all CpG sites in the region of interest
  3. c Adjusted for pyrosequencing run, child's age, child's birth weight, child's sex, maternal age, maternal education, and household income