Risks from not circumcising | Â | Â | Â |
---|---|---|---|
 |  | Fold increase | NNT †|
Urinary tract infection (infants) | 1++ | 10 | 50 |
Urinary tract infections (lifetime) | 2+ | 5 | 4 |
Pyelonephritis (infants) | 2+ | 10 | 100 |
- with concurrent bacteraemia | 2+ | 200 | 1000 |
- childhood hypertension | 2 | - | 1500 |
- end-stage renal disease (lifetime) | 2+ | - | 500 |
Candidiasis | 2 | 2 | 10 |
Prostate cancer | 2 | 1.5-2 | 6 |
Balanitis | 2++ | 3 | 10 |
Phimosis | 1++ | infinite | 10 |
High-risk HPV | 1++ | 3 | 2 |
Genital herpes (HSV-2) | 1+ | 1.35 | Â |
Syphilis | 1+ | 3 | 200 |
HIV infection | 1++ | 3-8 | 1000 |
Penile cancer | 1++ | > 20 | 1000 |
In female partner: | Â | Â | Â |
Cervical cancer | 1++ | 4 | - |
Chlamydia | 2+ | 4 | - |
HSV-2 | 2+ | 2 | - |
Bacterial vaginosis | 1+ | 2 | - |
Thus risk in an uncircumcised male of developing a condition requiring medical attention over their lifetime = 1 in 2 | |||
Risk associated with medical MC in infancy | Â | Â | Â |
Condition | Fold increase | NNH ††|  |
Local bruising at site of injection of local anesthetic (if dorsal penile nerve block used) | 0.25* | 4 | Â |
Infection, local | 0.002 | 600 | Â |
Infection, systemic | 0.0002 | 4000 | Â |
Excessive bleeding | 0.001 | 1000 | Â |
Need for repeat surgery (if skin bridges or too little prepuce removed) | 0.001 | 1000 | Â |
Loss of penis | close to 0 | 1 million | Â |
Death | close to 0 | Over 1 million | Â |
Loss of penile sensitivity | Low | High | Â |
Thus risk of an easily-treatable condition = 1 in 500 and of a true complication = 1 in 5000 |