| |
BSID-II (n = 684)
|
No BSID-II (n = 160)
| |
|---|
| |
N (%)
|
N (%)
|
p-value§
|
|---|
|
Median (IQR)
|
Median (IQR)
|
|---|
|
Inborn
|
654 (96%)
|
144 (90%)
|
0.005
|
|
Male gender
|
362 (53%)
|
89 (56%)
|
0.54
|
|
Gestational age [weeks]
|
26.7 (25.9-27.3)
|
27 (26.1-27.6)
|
0.007
|
|
Birth weight [gram]
|
855 (730–990)
|
940 (800–1100)
|
<0.001
|
|
SGA
|
52 (8%)
|
7 (5%)
|
0.15
|
|
Singleton
|
487 (71%)
|
121 (76%)
|
0.26
|
|
Antenatal corticosteroids (completed)
|
441 (69%)
|
99 (65%)
|
0.29
|
|
Caesarean delivery
|
552 (81%)
|
117 (73%)
|
0.028
|
|
SES score
|
6 (4–8)
|
6 (4–8)
|
0.72
|
|
Umbilical artery pH
|
7.31 (7.25-7.35)
|
7.30 (7.23-7.34)
|
0.17
|
|
PDA
|
311 (46%)
|
62 (39%)
|
0.12
|
|
PDA ligation
|
55 (8%)
|
15 (9%)
|
0.58
|
|
Mechanical ventilation
|
505 (79%)
|
109 (73%)
|
0.14
|
|
Mechanical ventilation [days]
|
4 (1–10)
|
4 (0–8)
|
0.20
|
|
Bronchopulmonary dysplasia
|
139 (21%)
|
18 (11%)
|
0.008
|
|
IVH > 2
|
46 (7%)
|
8 (5%)
|
0.42
|
|
Major brain injury
|
61 (9%)
|
10 (6%)
|
0.27
|
|
ROP stage 3 or higher
|
35 (5%)
|
8 (6%)
|
0.77
|
|
Proven sepsis
|
171 (25%)
|
32 (20%)
|
0.18
|
|
Necrotizing enterocolitis
|
18 (3%)
|
2 (1%)
|
0.30
|
-
§ p-value of Chi-square test (for ratios) and p-value of Mann–Whitney U test (for linear variables); IQR, interquartile range; IVH, intraventricular haemorrhage; NEC, necrotizing enterocolitis; PDA, persistent ductus arteriosus; ROP, retinopathy of prematurity; SES, socioeconomic score; SGA, small for gestational age (<10th percentile).
