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Table 3 Multivariate Cox regression analysis of predictors of mortality among Children on ART at Felege Hiwot referral hospital, January 1 st , 2006 - March 31 st , 2011

From: Predictors of mortality among children on Antiretroviral Therapy at a referral hospital, Northwest Ethiopia: A retrospective follow up study

Variable Survival status Crude HR (95% CI) Adjusted HR (95% CI)
  Died Censored   
Age     
  < 1yr 4 18 1  
  1-5 yr 10 187 0.25(0.08, 0.79) *
  5 -15 yr 27 303 0.38(0.13, 1.09) *
Sex     
  Male 17 269 0.66 (0.35, 1.22) *
  Female 24 239 1  
OIs     
  Yes 20 145 2.01 (1.09, 3.72) *
  No 21 363 1  
Cotrimoxazole preventive therapy     
  Yes 8 279 1 1
  No 33 229 4.89(2.26,10.59) 4.74 (2.17, 10.34)
Developmental history     
  Appropriate 34 497 1 1
  Delayed/regressing 7 11 10.13(4.43, 23.1) 6.31(2.52, 15.83)
WHO staging     
  I/II 8 165 0.28(0.11, 0.72) *
  III 23 294 0.43(0.21, 0.91) *
  IV 10 49 1  
Haemoglobin (n = 520)     
  <10gm/dl 15 88 2.87(1.5, 5.5) 2.44 (1.26, 4.73)
  ≥10gm/dl 24 393 1 1
Nutritional status     
  Underweight 39 414 3.89(0.94, 16.1) *
  Normal 2 94 1  
CD4 cell count     
  CD4 count below the threshold 30 259 2.55(1.28, 5.1) 2.24(1.07, 4.69)
  CD4 count above the threshold 11 249 1 1
  1. * Non significant from the multivariate Cox regression (Backward LR method).