Table 2 Details of microbiology results and management in 10 children with a confirmed diagnosis of CNS infection
Final diagnosis | CSF WCC cells/ml | CSF glucose mmol/L (CSF/plasma ratio) | CSF PCR | Blood cultures | Treatment | Duration (days) | Microbiology/ID advice sought? |
|---|---|---|---|---|---|---|---|
Aseptic Meningitis | 8 | 4.5 (no plasma glucose) | Negative | Negative | cephalosporin | 4 | Yes |
28 | 3.9 (no plasma glucose) | Negative | Escherichia coli | cephalosporin | 3 | Yes | |
20 | 2.9 (no plasma glucose) | Not done | Negative | cephalosporin | 2 | Yes | |
130 | 3.7 (0.62) | Not done | Negative | cephalosporin | 21 | Yes | |
Purulent Meningitis | Blood stained | Blood stained | Not done | Haemophillus influenzae type b | cephalosporin | 9 | Yes |
aciclovir | 1 | ||||||
632 | 4.7 (0.76) | Negative | Group B Neisseria meningitidis | cephalosporin | 12 | Yes | |
112 | 0.17 (0.03) | Negative | Negative | cephalosporin | 7 | Yes | |
Encephalitis | 0 | 2.7 (0.44) | Adeno virus species | Negative | aciclovir | 8 | No |
cephalosporin | 8 | ||||||
0 | 5.2 (no plasma glucose) | Herpes Simplex Virus 1 | Negative | aciclovir | 7 | No | |
cephalosporin | 7 | ||||||
7.2 (lymphocytosis) | 3.6 (0.56) | Herpes Simplex Virus 1 | Negative | aciclovir | 14 | Yes | |
cephalosporin | 2 |