Pregnancy loss and role of infant HIV status on perinatal mortality among HIV-infected women

BMC Pediatrics

Table 6 Sensitivity analyses for the 50 infants with unknown HIV status

MTCT	No.	Neonatal morality			Early mortality
		Mortality Rate (n)	Crude HR (95% CI)	Adjusted HR(95% CI)^e	Mortality Rate (n)	Crude HR (95% CI)	Adjusted HR(95% CI)^f
Model 1 ^a
IU	64	0.050 (3)	1.09 (0.34–3.50)	0.97 (0.30–3.18)	0.137 (8)	2.26 (1.08–4.73)	1.65 (0.77–3.50)
IP/ePP	64	0.016 (1)	0.35 (0.05–2.51)	0.39 (0.05–2.85)	0.048 (3)	0.78 (0.25–2.50)	1.11 (0.35–3.58)
NI at least for 42 days	1004	0.044 (43)	1.0		0.059 (56)	1.0
Model 2 ^b
IU	114	0.268 (26)	14.82 (8.25–26.60)	12.03 (6.45–22.42)	0.347 (32)	12.65 (7.73–20.72)	8.15 (4.83–13.74)
IP/ePP	64	0.016 (1)	0.73 (0.10–5.40)	0.73 (0.10–5.47)	0.048 (3)	1.34 (0.41–4.39)	1.70 (0.52–5.58)
NI at least for 42 days	954	0.022 (20)	1.0		0.035 (32)	1.0
Model 3 ^c
IU	64	0.050 (3)	2.28 (0.68–7.68)	1.88 (0.55–6.43)	0.137 (8)	3.89 (1.79–8.44)	2.70 (1.23–5.91)
IP/ePP	114	0.238 (24)	13.15 (7.25–23.84)	11.65 (6.23–21.79)	0.275 (27)	9.92 (5.93–16.58)	9.61 (5.58–16.54)
NI at least for 42 days	954	0.022 (20)	1.0		0.035 (32)	1.0
Model 4 ^d
IU	67	0.080 (5)	1.94 (0.77–4.93)	1.66 (0.65–4.29)	0.164 (10)	2.98 (1.52–5.87)	2.09 (1.05–4.17)
IP/ePP	67	0.045 (3)	1.13 (0.35–3.65)	0.82 (0.20–3.41)	0.076 (5)	1.39 (0.56–3.48)	1.55 (0.56–4.32)
NI at least for 42 days	998	0.040 (39)	1.0		0.055 (52)	1.0

^a Assume all of the 50 infants as NI at least for 42 days.
^b Assume all of the 50 infants infected by IU transmission.
^c Assume all of the 50 infants infected by IP/ePP transmission.
^d HIV status of the 50 infants was imputed based on the predicted probability of HIV transmission.
^e Adjusted for stopping breastfeeding, LBW, and preterm birth.
^f Adjusted for stopping breastfeeding, LBW, and 2+ children (5–16 aged).

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