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Table 1 Pain assessed with CRIES and PIPP scores 30 seconds following ROP screening examination with WFDRI (n = 35) and BIO (n = 35)

From: Pain and stress assessment after retinopathy of prematurity screening examination: Indirect ophthalmoscopy versus digital retinal imaging

Time CRIES score PIPP score
WFDRI BIO Difference in pain score (BIO-WFDRI) from baseline WFDRI BIO Difference in pain score (BIO-WFDRI) from baseline:
Mean (SD) Mean (SD) pvalue Mean (SD) Mean (SD) pvalue
Baseline 0.4 (0.7) 0.2 (0.5) - 4.1 (1.1) 4.0 (1.0) -
30s after 1.6 (1.1) 2.5 (1.4) 0.000 6.2 (1.9) 7.4 (2.3) 0.006
1 h after 0.4 (0.6) 0.3 (0.6) 0.79 5.1 (1.2) 4.7 (1.0) 0.16
24 h after 0.3 (0.4) 0.1 (0.4) 0.62 4.7 (0.7) 4.7 (0.9) 0.75
  1. Abbreviations: CRIES score, Crying, Requires oxygen, Increased vital signs, Expression and Sleeplessness; PIPP score, Premature Infant Pain Profile; ROP, retinopathy of prematurity; WFDRI, wide-field digital imaging; BIO, Binocular indirect ophthalmoscopy; SD, standard deviation; s = seconds; h = hours.