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Table 3 Suggested safety measures during IS treatment with ACTH and vigabatrin

From: Infantile spasms (West syndrome): update and resources for pediatricians and providers to share with parents

 

ACTH

Vigabatrin

Baseline hematology

X

X

Baseline serum chemistries (i.e., SMA 20)

X

X

Day 3 serum chemistries (especially potassium)

X

 

Twice weekly:

  

Blood pressure

X

 

Stool guaiac

X

 

Urine glucose

X

 

Periodic ophthalmic evaluations and visual history

 

X

Periodic clinical exam and review of potential side effects

X

X