Growth restriction in gastroschisis: quantification of its severity and exploration of a placental cause

BMC Pediatrics

Table 5 Placental findings associated with gastroschisis

Placental findings	Controls N = 29	Gastroschisis N = 31	p-value
Placental weight z-score (mean ± sd)^a	0.24 ± 1.29	-0.03 ± 1.07	0.804^b
Chorioamnionitis (%)	14 (48)	13 (42)	0.796^c
Any chorangiosis (%)^d	12 (41)	25 (81)	0.003^c
Focal chorangiosis (%)^d	8 (28)	12 (39)	0.419^c
Diffuse chorangiosis (%)^e	4 (14)	13 (42)	0.022^c

^a Excludes the placentas of patients who were SGA (n = 9), had hydrops (n = 5), or both (n = 3).
^b Rank-sum test
^c Fisher exact test
^d Focal chorangiosis was defined as ≥ 10 capillaries in ≥ 10 terminal villi in 10 fields at 10× magnification in each of 1-2 areas (slides).
^e Diffuse chorangiosis was defined as ≥ 10 capillaries in ≥ 10 terminal villi in 10 fields at 10× magnification in each of 3 areas (slides).

ISSN: 1471-2431