BMC Pediatrics

Table 2 Unadjusted and adjusted analysis of birth weight among gastroschisis patients and Controls

From: Growth restriction in gastroschisis: quantification of its severity and exploration of a placental cause

		Unadjusted			Adjusted
	Coefficient^a	95% CI^b	p-value	Coefficient^c	95% CI^b	p-value
Gastroschisis	-350	-415, -286	<0.001	-317	-415, -218	<0.001
Gestational age (weeks)	228	213, 244	<0.001	ND^c	ND	ND
Male gender	107	-39, 253	0.151	ND^c	ND	ND
Multiple gestation	-241	-391, -92	0.002	ND^c	ND	ND
Maternal race/ethnicity
White	Referent			Referent
African American	-250	-363, -136	<0.001	-236	-368, -104	0.001
Native American	1	-429, 431	0.996	277	-181, 735	0.235
Asian	-219	-344, -95	0.001	-178	-301, -55	0.005
Hispanic	-182	-480, 115	0.229	-178	-510, 155	0.292
Gestational diabetes	134	-53, 323	0.160	77	-106, 260	0.407
Pre-existing diabetes	628	348, 908	<0.001	689	406, 973	<0.001
Maternal smoking	-220	-313, -128	<0.001	-142	-249, -34	0.010
Maternal hypertension	-251	-372, -129	<0.001	-354	-473, -234	<0.001
Maternal illicit drug use	-378	-545, -211	<0.001	-255	-453, -58	0.012
Maternal alcohol use	-390	-603, -176	0.005	-143	-358, 71	0.189
Single mother	-234	-316, -152	<0.001	-59	-161, 42	0.250
Maternal age (years)	13	7, 18	<0.001	-2	-9, 6	0.654
Nullipara	-164	-246, -82	<0.001	-98	-192, -6	0.037
Outborn (yes = 1, no = 0)	239	141, 337	<0.001	136	42, 230	0.005
Era (1999-2007)	1	-72, 74	0.980	27	-44, 98	0.452

^a Obtained by univariate regression
^b CI= 95% confidence interval
^c Adjusted coefficient obtained by multiple regression. Since cases and controls were perfectly matched for gestational age, gender, and multiple gestation, these variables were not included in the multiple regression analyses. All other potential covariates were included (see methods).

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