Feature | Gastroschisis (n = 179) number (%) | Controls (n = 895) number (%) | p-valuea |
---|---|---|---|
Gestational age (weeks) (mean ± sd) | 36 ± 2 | 36 ± 2 | 1.000 |
Maternal age (years) (mean ± sd) | 22 ± 4 | 30 ± 3 | <0.001 |
   Age ≤ 20 years (%) | 69 (38.6) | 44 (5.0) |  |
   Age 20-24 years (%) | 70 (39.1) | 154 (17.2) |  |
   Age 25-29 years (%) | 31 (17.3) | 248 (27.7) |  |
   Age ≥ 30 years (%) | 9 (5.0) | 449 (50.2) |  |
Maternal race | Â | Â | <0.001 |
   Caucasian (%) | 140 (78.2) | 741 (82.8) |  |
   African American (%) | 7 (3.9) | 90 (10.1) |  |
   Asian (%) | 19 (10.6) | 38 (4.3) |  |
   Hispanic (%) | 8 (4.5) | 20 (2.2) |  |
   Native American (%) | 5 (2.8) | 6 (0.7) |  |
Female | 84 (47.0) | 420 (47.0) | 1.000 |
Inborn (%) | 155 (86.6) | 697 (77.9) | 0.008 |
Birth weight <10th centileb (%) | 44 (24.6) | 69 (7.7) | <0.001 |
Gestational hypertension/pre-eclampsia (%) | 0 | 148 (16.5) | N/Ae |
Single (%) | 113 (63.1) | 224 (25.0) | <0.001 |
Minor anomalies (%) | 24 (13.4) | 39 (4.4) | <0.001 |
Multiple gestation | 4 (2.2) | 20 (2.2) | 1.000 |
Primigravida | 110 (61.5) | 285 (31.8) | <0.001 |
Gestational diabetesf | 1 (0.6) | 63 (7.3) | 0.010 |
Pre-existing (before pregnancy) diabetesf | 0 | 27 (3.3) | N/Ae |
Maternal smoking | 52 (29.1) | 138 (15.4) | <0.001 |
Maternal illicit drug use | 7 (3.9) | 32 (3.6) | 0.829 |
Maternal alcohol use | 7 (3.9) | 16 (1.8) | 0.082 |
Center (Minneapolis) | 155 (86.6) | 767 (85.7) | 0.754 |
Era (1999-2007) | 129 (72.1) | 581 (64.9) | 0.065 |
Birth weight (g) | 2400 ± 502 | 2750 ± 532 | <0.001 |
Birth weight z-score | -0.65 ± 0.86 | 0.11 ± 0.49 | <0.001 |
Crown-heel length (cm) | 45.7 ± 3.3 | 48.4 ± 2.7 | <0.001 |
Crown-heel length z-scorec,d | -0.50 ± 1.19 | 0.68 ± 0.55 | <0.001 |
Occipitofrontal circumference (OFC) | 31.9 ± 1.9 | 32.9 ± 1.6 | <0.001 |
OFC z-scored (cm) | -0.36 ± 0.87 | 0.24 ± 0.45 | <0.001 |
Ponderal index | 2.51 ± 0.37 | 2.40 ± 0.16 | <0.001 |
Ponderal index z-score | -0.06 ± 0.85 | -0.30 ± 0.34 | <0.001 |