Table 2 Fluids Administered and [Na] changes
| Â | 0.9% saline | 0.45% saline | P-value* |
|---|---|---|---|
Fluid Administration (median [IQR]) | |||
Hours of study fluid administration | 12 [10, 12.7] | 11.9 [11.6, 12.3] | 0.97 |
Rate (as % traditional maintenance rate) | 105 [95,141] | 104 [99,123] | 0.80 |
Additional isotonic fluids (ml/kg) | 7.4 [3.4, 18.6] | 8.6 [2.8, 19.3] | 0.84 |
Oral fluids (ml/kg) | 4.7 [0.2, 8.3] | 0 [0,6] | 0.14 |
Free water (ml/kg) | 4.7 [0.7, 8.3] | 16.5 [12, 29.5] | 0.00 |
Free water (% of total fluids received) | 12 [1,20] | 45 [37,64] | 0.00 |
[Na] Data (median [IQR]) | |||
Rate of change [Na] (mmol/L/hr) | +0.20 [0.03, 0.4] | +0.08 [-0.15, 0.16] | 0.12 |
Absolute change in [Na] (mmol/L) | +3.0 [0.5, 4.5] | +1.0 [0.0, 2.0] | 0.14 |
Exit [Na] (mmol/L) | 140 [138,141] | 138 [136,139] | 0.10 |
[Na] Data (number (%)) | |||
No. of patients with a fall in [Na] (%) | 3 (19) | 5 (24) | 0.7 |
No. of patients with exit Na < 136 mmol/L (%) | 1 (6) | 1 (5) | 1 |