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Table 4 Receiver Operating Characteristic (ROC) curves of combinations of clinical findings with the greatest area under the curve (AUC), and sensitivity and specificity of various cut-off numbers of findings in predicting HIV-infection among exposed infants.

From: Utility of clinical parameters to identify HIV infection in infants below ten weeks of age in South Africa: a prospective cohort study

One of a combination of oral thrush, any lymphadenopathy, hepatomegaly, splenomegaly, plus: ROC AUC Findings present Sensitivity (%) Specificity (%)
A: weight < 15th centile, diaper dermatitis 0.754 1 77.9 61.2
   2 47.7 88.0
   3 25.2 98.4
B: weight < 50th centile, diaper dermatitis 0.717 1 88.9 29.6
   2 48 90.4
   3 20.6 99.2
C: weight < 3rd centile, reflux 0.744 1 63.8 80
   2 31.4 97.6
   3 12.5 100
One of a combination of oral thrush, diaper dermatitis, plus: ROC AUC Findings present Sensitivity (%) Specificity (%)
D: weight < 3rd centile 0.682 1 60.7 72
   2 28.3 92.8
   3 4.8 100
E: weight < 50th centile 0.666 1 84.7 30.4
   2 46.8 82.4