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Table 1 Risk of infection classification categories

From: Neonatal Procalcitonin Intervention Study (NeoPInS): Effect of Procalcitonin-guided decision making on Duration of antibiotic Therapy in suspected neonatal early-onset Sepsis: A multi-centre randomized superiority and non-inferiority Intervention Study

Category 4:
Low risk
(Infection unlikely)
One abnormal finding:
  - pre/perinatal risk factor*, OR
  - suspect clinical symptom*, OR
  - abnormal laboratory examination*
Category 3:
Intermediate risk
(Infection possible)
Two abnormal findings:
  - pre/perinatal risk factors*, AND/OR
  - suspect clinical symptoms*, AND/OR
  - abnormal laboratory examinations*
Category 2:
High risk
(Infection probable)
Three abnormal findings:
  - pre/perinatal risk factors*, AND/OR
  - suspect clinical symptoms*, AND/OR
  - abnormal conventional laboratory examinations*
Category 1:
Proven infection
≥ 1 abnormal finding (pre/perinatal risk factors, clinical symptoms, laboratory examinations) AND a positive culture
  1. The assessment of risk of infection classification is independent of serum PCT levels.
  2. * See assessment guidelines (Table 2)