The first three years of screening for medium chain acyl-CoA dehydrogenase deficiency (MCADD) by newborn screening ontario

Table 1 Characteristics of infants who screened positive for MCADD

	N (percent)	Median C8 (uM)	Mean C8 (uM)
Sex (n = 73)*
Male	40 (55)	0.55	3.65
Female	33 (45)	1.40	5.18
Gestational age (n = 61)
< = 37 weeks	12 (20)	0.49	3.93
> 37 weeks	49 (80)	0.75	4.09
Birthweight (n = 65)
< 2500 grams	10 (15)	0.49	4.70
> = 2500 grams	55 (85)	0.62	3.70
Reported feeding status at time of screen (n = 63)
Breastfeeding	47 (75)	0.62	3.54
Partial breastfeeding	6 (10)	0.71	3.87
Formula or other (e.g., total parenteral nutrition)	10 (16)	0.94	5.98

* Note: sample sizes differ for sub-sample analyses because of missing data on the blood spot requisition forms (n = 74, median C8 0.68 uM, mean C8 4.29 uM, range 0.33-30.41 uM)

ISSN: 1471-2431