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Table 2 WHO-recommended regimens for infants and children

From: The global pediatric antiretroviral market: analyses of product availability and utilization reveal challenges for development of pediatric formulations and HIV/AIDS treatment in children

Year of WHO Guideline

First-Line Regimen

Second-Line Regimen

2002

ZDV + 3TC + ABC

d4T + ddI + PI* or d4T + ddI + (EFV or NVP)

 

ZDV + 3TC + (NVP or EFV)

d4T + ddI + PI*

2006 Preferred

(ZDV or d4T) + 3TC + (NVP or EFV)

ddI + ABC + PI**

 

ABC + 3TC + (NVP or EFV)

ddI + ZDV + PI**

2006 Alternative

(ZDV or d4T) + 3TC + ABC

ddI + (EFV or NVP) +PI**

2008***

(ZDV or d4T or ABC) + 3TC + NVP

 
 

(ZDV or d4T or ABC) + 3TC + LPV/r

 
  1. *PI options include LPV/r and NFV
  2. **PI options include LPV/r, SQV/r, and NFV
  3. ***Infants <12 months of age
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BMC Pediatrics

ISSN: 1471-2431

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