| Time | HSD/5D (n = 26) | RL (n = 29) | p |
---|---|---|---|---|
PRIMARY OUTCOMES | Â | Â | Â | Â |
Number with shock, n/N(%) | 8 h | 15/22(68) | 14/25(56) | 0.39 |
 | 24 h | 14/18(78) | 14/25(56) | 0.14 |
Oliguria (<1 ml/kg/hour), n/N(%) | 8 h | 9/22(41) | 3/25(12) | 0.02 |
 | 24 h | 8/18(44) | 6/25(24) | 0.16 |
Tachycardia (>160 bpm), n/N(%) | 8 h | 6/22(27) | 4/25(16) | 0.34 |
 | 24 h | 8/14(44) | 4/25(16) | 0.04 |
Creatinine, mean(± standard deviation) | 8 h | 112(85) | 104(60) | 0.73 |
 | 24 h | 89(56) | 112(87) | 0.39 |
SECONDARY OUTCOMES | Â | Â | Â | Â |
Tachypnoea (>60 br.pm), n/N(%) | 8 h | 7/22(32) | 2/25(8) | 0.04 |
 | 24 h | 7/18(39) | 3/25(12) | 0.04 |
Base deficit, mean(± standard deviation) | 8 h | 10(13) | 15(7) | 0.16 |
 | 24 h | 12(8) | 8(9) | 0.38 |
In-hospital mortality, n/N (%) | Â | 15/26(58) | 13/29(45) | 0.34 |