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Table 2 Primary and Secondary outcomes

From: Phase II trial of isotonic fluid resuscitation in Kenyan children with severe malnutrition and hypovolaemia

 

Time

HSD/5D (n = 26)

RL (n = 29)

p

PRIMARY OUTCOMES

    

Number with shock, n/N(%)

8 h

15/22(68)

14/25(56)

0.39

 

24 h

14/18(78)

14/25(56)

0.14

Oliguria (<1 ml/kg/hour), n/N(%)

8 h

9/22(41)

3/25(12)

0.02

 

24 h

8/18(44)

6/25(24)

0.16

Tachycardia (>160 bpm), n/N(%)

8 h

6/22(27)

4/25(16)

0.34

 

24 h

8/14(44)

4/25(16)

0.04

Creatinine, mean(± standard deviation)

8 h

112(85)

104(60)

0.73

 

24 h

89(56)

112(87)

0.39

SECONDARY OUTCOMES

    

Tachypnoea (>60 br.pm), n/N(%)

8 h

7/22(32)

2/25(8)

0.04

 

24 h

7/18(39)

3/25(12)

0.04

Base deficit, mean(± standard deviation)

8 h

10(13)

15(7)

0.16

 

24 h

12(8)

8(9)

0.38

In-hospital mortality, n/N (%)

 

15/26(58)

13/29(45)

0.34