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Table 4 Baseline factors associated with successful treatment outcome (VS/IS)

From: Growth, immune and viral responses in HIV infected African children receiving highly active antiretroviral therapy: a prospective cohort study

Baseline characteristic

Unadjusted OR (95% CI)

Adjusted OR (95% CI)†

Age

> 18 months (vs < 18 mths)

1.07 (0.39 - 2.96)

4.6 (1.14 -19.1)*

Sex

Male (vs Female)

0.91 (0.44 - 1.91)

0.71 (0.27 - 1.85)

CD4 cell %

>10% (vs ≤ 10%)

7.04 (3.07 - 16.19)**

6.97 (2.6 - 18.6)**

HIV-1 RNA (copies/ml)

< 750,000 (vs ≥ 750,000)

1.95 (0.51 - 7.51)

1.42 (0.29 - 6.98)

WHO stage

1&2 (vs 3)

2.21 (0.93 - 5.24)

3.50 (1.05 - 12.7)*

WAZ

≤ -2 (vs ≥ -2)

0.48 (0.20 -1.13)

0.50 (0.14 -1.78)

HAZ

≤ -2 (vs > -2)

0.79 (0.38 - 1.66)

1.19 (0.39 - 3.65)

  1. †Adjusted for age, sex, CD4 cell %, viral load, WHO stage, WAZ and HAZ. **p < 0.0001 *p = < 0.05. HAZ = Height for age z score, WAZ = weight for age z score and WHO = World Health Organization.