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Table 1 Demographic characteristics of the 1646 community-acquired cases of rotavirus gastroenteritis presenting to CHOP in the pre-vaccine eraâ—Š between the 1994-95 and 2005-06 epidemic seasons

From: Unexpectedly high burden of rotavirus gastroenteritis in very young infants

Rotavirus season

Number of cases

Median age§[IQR] (months)

Predominant serotype‡

% male¶

% urban residents

% non-white race#

1994-1995

178

8

[4 - 16]

G3

61%

majority unknown

47%

28% unknown

1995-1996

155

9

[4 - 16]

G9, G2

58%

70%

5% unknown

78%

2% unknown

1996-1997

115

9

[6 - 17.25]

G1

66%

majority unknown

52%

11% unknown

1997-1998

84

11.5

[6 - 24]

G1

55%

majority unknown

26%

49% unknown

1998-1999

166

10

[4 - 19.5]

G2, G1

57%

majority unknown

59%

11% unknown

1999-2000

94

11

[4.75 - 22]

G1 (47%)

G9 (41%)

53%

66%

67%

2000-2001

115

14

[7 - 22]

G1 (95%)

62%

79%

50%

2001-2002

92

11

[6.25 - 19]

G1 (94%)

58%

44%

58%

2002-2003

29†

11

[5.5 -17]

G1 (97%)†

55%

48%

55%

2003-2004

158

13

[7 - 26.25]

G1 (69%)

G12 (11%)

52%

47%

49%

2004-2005

185

14

[7 - 22]

G1 (87%)

53%

48%

55%

2005-2006

275

11

[5 - 25]

G1 (51%)

G3 (39%)

59%

55%

70%

  1. â—ŠA tetravalent rotavirus vaccine had been transiently available in the United States in 1998-99.
  2. §Age was not recorded for 5 children. The median [IQR] age for the other 1641 children seen at CHOP during the 12 rotavirus epidemic seasons combined was 11 (5 - 21) months.
  3. ‡From 1994-95 to 1998-99, serotypes were based on electropherotypes compared to CDC standards. Starting with the 1999-2000 season, serotypes were determined by RT-PCR genotyping.
  4. ¶Excludes 6 children where the gender was not recorded.
  5. #The "non-white" category potentially includes children of African, Asian, Hispanic, Eskimo, and Native American heritage.
  6. †Due to a laboratory accident, only 29 specimens from the 175 cases in the 2002-2003 rotavirus season were suitable for genotyping.