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Table 4 Risk factors for mortality related to disease/treatment in the neonatal period

From: Determinants of survival in very low birth weight neonates in a public sector hospital in Johannesburg

Risk factor (Valid cases)

 

Total

Survived (%)

Died (%)

P Value

Odds ratio

95% CI of Odds Ratio

HMD (437)

Yes

299

190 (63.5)

109 (36.5)

< 0.001

0.33

0.20 - 0.55

 

No

138

116 (84.1)

22 (15.9)

   

Mechanical ventilation (474)

Yes

99

71 (71.7)

28 (28.3)

0.76

1.08

0.66 - 1.76

 

No

375

263 (70.1)

112 (29.9)

   

Nasal CPAP (474)

Yes

96

80 (83.3)

16 (16.7)

0.002

2.44

1.37 - 4.35

 

No

378

254 (67.2)

124 (32.8)

   

Surfactant therapy (474)

Yes

90

73 (81)

17 (19)

0.014

2.02

1.15 - 3.58

 

No

384

261 (68)

123 (32)

   

Sepsis (445)

Yes

62

40 (64.5)

22 (35.5)

0.085

0.61

0.34 - 1.08

 

No

383

287 (74.9)

96 (25.1)

   

Gram Negative (474)

Yes

37

21 (56.8)

16 (43.2)

0.057

0.52

0.26 - 1.03

 

No

437

313 (71.6)

124 (28.4)

   

Gram Positive (474)

Yes

28

23 (82.1)

5 (17.9)

0.163

1.99

0.74 - 5.36

 

No

446

311 (69.7)

135 (30.3)

   

PDA (474)

Yes

26

18 (69)

8 (31)

0.887

0.94

0.4 - 2.21

 

No

448

316 (71)

132 (29)

   

Hypotension (474)

Yes

23

7 (30)

16 (70)

< 0.001

0.166

0.07 - 0.41

 

No

451

327 (73)

124 (27)

   

NEC grade 2/3 (474)

Yes

26

9 (35)

17 (65)

< 0.001

0.2

0.09 - 0.46

 

No

448

325 (73)

123 (27)

   

IVH (328)

    

0.004

  
 

No

253

209 (83)

44 (17)

 

1

 
 

Gr 1

11

8 (72.7)

3 (27.3)

 

0.56

0.14 - 2.20

 

Gr 2

40

25 (62.5)

15 (37.5)

 

0.35

0.17 - 0.72

 

Gr 3

16

12 (75)

4 (25)

 

0.63

0.19 - 2.05

 

Gr 4

4

1 (25)

3 (75)

 

0.07

0.01 - 0.69

 

PVL

4

2 (50)

2 (50)

 

0.21

0.03 - 1.53

  1. Note: Valid cases = those with no missing data
  2. Percentages are reported for rows